| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5106060 | B | Inhibition of Clostridium botulinum BoNT/A light chain (1 to 424 residues) using SNAPtide as substrate by FRET assay | Clostridium botulinum | 10 | single protein format | Scientific Literature | ||
| 2. | ALA5106062 | F | Protection against BoNT/A induced toxicity in mouse model assessed as survival rate at 2.5 mg/kg, ip preincubated with BoNT/A for 30 mins followed by administration into mouse and measured after 12 hrs (Rvb = 70%) | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 3. | ALA5106063 | F | Protection against BoNT/A induced toxicity in mouse model assessed as survival rate at 2.5 mg/kg, ip preincubated with BoNT/A for 30 mins followed by administration into mouse and measured after 24 hrs relative to control | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 4. | ALA5106064 | F | Protection against BoNT/A induced toxicity in mouse model assessed as improvement in survival rate at 2.5 mg/kg, ip preincubated with BoNT/A for 30 mins followed by administration into mouse and measured after 72 hrs | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 5. | ALA5106068 | B | Binding affinity to Clostridium botulinum BoNT/A light chain (1 to 424 residues) assessed as modification at Cys165 residue by measuring increase in molecular weight of reaction product at 500 uM incubated for 0.5 hrs by mass spectrometry analysis | Clostridium botulinum | 9 | single protein format | Scientific Literature |
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