# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5148065 | F | Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence of IBMX by cAMP assay | Homo sapiens | 15 | ALA5143691 | cell-based format | Scientific Literature | |
2. | ALA5148066 | A | Metabolic stability in rat liver microsomes assessed as compound remaining at 1 uM incubated for 30 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 15 | ALA5143691 | microsome format | Scientific Literature | |
3. | ALA5148067 | P | Aqueous solubility of the compound in pH 1.2 JP1 fluid measured after 4 hrs by HPLC-UV analysis | 14 | ALA5143691 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5148068 | P | Aqueous solubility of the compound in pH 6.8 JP2 fluid measured after 4 hrs by HPLC-UV analysis | 14 | ALA5143691 | small-molecule physicochemical format | Scientific Literature |