# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5161043 | F | Induction of cell cycle arrest in human SK-OV-3 cells assessed as accumulation at G1 phase at 1 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA5161044 | F | Induction of apoptosis in human H1975 cells assessed as late apoptotic cells at 0.1 uM incubated for 24 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 3.9 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA5161045 | B | Inhibition of PDGFR-beta (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
4. | ALA5161046 | B | Inhibition of c-Kit (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
5. | ALA5161047 | B | Inhibition of PDGFR-alpha (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA5161048 | T | Toxicity in nude BALB/c mouse xenografted with human A-431 cells assessed as body weight loss at 20 mg/kg measured after 21 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
7. | ALA5161049 | B | Inhibition of human wild type EGFR phosphorylation in human NCI-H1975 cells at 1 nM by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA5161050 | B | Inhibition of human wild type EGFR phosphorylation in human A-431 cells at 1 nM by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5161051 | B | Inhibition of wild-type EGFR (14 to 721 residues) (unknown origin) by western blot analysis | Homo sapiens | 28 | single protein format | Scientific Literature | ||
10. | ALA5161054 | B | Inhibition of recombinant human EGFR L858R/T790M double mutant using GGMEDIYFEFMGG as substrate in presence of ATP by radiometric assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
11. | ALA5161055 | B | Inhibition of ERK phosphorylation in human NCI-H1975 cells at 1 to 1000 nM by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA5161056 | B | Inhibition of ERK phosphorylation in human A-431 cells at 1 to 1000 nM by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA5161057 | B | Inhibition of AKT phosphorylation in human NCI-H1975 cells at 1 to 1000 nM by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA5161058 | B | Inhibition of AKT phosphorylation in human A-431 cells at 1 to 1000 nM by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5161059 | B | Inhibition of SRC (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
16. | ALA5161060 | B | Inhibition of HER2 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
17. | ALA5161061 | B | Inhibition of HER4 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
18. | ALA5161062 | B | Inhibition of VEGFR2 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
19. | ALA5161063 | B | Inhibition of EPH-A2 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
20. | ALA5161064 | B | Inhibition of IGF1R (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature |