# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5151839 | B | Binding affinity to N-terminal His-tagged and C-terminal Avi-tagged full length human WDR5 WIN site expressed in Escherichia coli assessed as residence time by Surface plasmon resonance assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
2. | ALA5151840 | B | Inhibition of human N-terminal His tagged MLL1(3745 to 3969)/WDR5 (22 to 334)/RbBP5 (1 to 538)/ASH2L (2 to 534)/DPY-30 (1 to 99) complex expressed in Escherichia coli assessed as decrease in methyltransferase activity preincubated with WRAD2 complex for 15 mins followed by substrate addition and measured after 1 hr using nucleosome peptide as substrate in presence of H3-SAM by scintillation counter analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
3. | ALA5151841 | B | Binding affinity to N-terminal His-tagged and C-terminal Avi-tagged full length human WDR5 WIN site expressed in Escherichia coli measured upto 600 sec by Surface plasmon resonance assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
4. | ALA5151842 | F | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation incubated for 4 days by ATPlite assay | Homo sapiens | 1 | cell-based format | Scientific Literature |