| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5167616 | B | Inhibition of mouse Spns2 transfected in human HeLa cells by measuring S1P release by LC/MS analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5167617 | B | Inhibition of mouse Spns2 transfected in human HeLa cells by measuring S1P release at 2 uM by LC/MS analysis relative to control | Mus musculus | 60 | cell-based format | Scientific Literature | ||
| 3. | ALA5167618 | B | Inhibition of recombinant mouse SphK1 transfected in HEK293T cells using D-erythro-sphingosine measured after 20 mins in presence of gamma-[p32]-ATP by autoradiography and liquid scintillation counting method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5167619 | B | Inhibition of recombinant mouse SphK2 transfected in HEK293T cells using D-erythro-sphingosine measured after 20 mins in presence of gamma-[p32]-ATP by autoradiography and liquid scintillation counting method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5167620 | B | Selectivity ratio of IC50 for mouse SphK1 to recombinant mouse Snps2 | Mus musculus | 1 | assay format | Scientific Literature | ||
| 6. | ALA5167621 | B | Selectivity ratio of IC50 for mouse SphK2 to recombinant mouse Snps2 | Mus musculus | 1 | assay format | Scientific Literature | ||
| 7. | ALA5167622 | F | In vivo inactivation of Spns2 gene in C57BL/6j mouse assessed as decrease in circulating lymphocytes at 20 mg/kg, ip measured after 4 hrs by blood analyzer | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA5167623 | F | In vivo inactivation of Spns2 gene in C57BL/6j mouse assessed as decrease in plasma S1P at 20 mg/kg, ip measured after 4 hrs by by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA5167624 | A | Half life in Sprague-Dawley rat plasma at 10 mg/kg, ip by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA5167625 | A | Drug concentration in Sprague-Dawley rat plasma at 10 mg/kg, ip at 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA5167626 | A | Drug concentration in Sprague-Dawley rat plasma at 10 mg/kg, ip at 2 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA5167627 | F | In vivo inactivation of Spns2 gene in Sprague-Dawley rat assessed as decrease in circulating lymphocytes at 10 mg/kg, ip measured upto 24 hrs by blood analyzer | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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