# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5135838 | F | Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay | Homo sapiens | 104 | cell-based format | Scientific Literature | ||
2. | ALA5135839 | F | Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as maximal Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay relative to control | Homo sapiens | 98 | cell-based format | Scientific Literature | ||
3. | ALA5135840 | F | Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay | Homo sapiens | 104 | cell-based format | Scientific Literature | ||
4. | ALA5135841 | F | Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as maximal Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay relative to control | Homo sapiens | 94 | cell-based format | Scientific Literature | ||
5. | ALA5135842 | B | Selectivity index, log ratio of Emax for agonist activity at human 5HT2C receptor expressed in Flp-In-T-REx-293 cells to EC50 for agonist activity at human 5HT2A receptor expressed in Flp-In-T-REx-293 cells | Homo sapiens | 90 | cell-based format | Scientific Literature | ||
6. | ALA5135843 | F | Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
7. | ALA5135844 | F | Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as maximal Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
8. | ALA5135845 | B | Binding affinity to 5HT2C receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | single protein format | Scientific Literature | ||
9. | ALA5135847 | B | Inhibition of 5HT3 receptor (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA5135848 | B | Binding affinity to 5HT5A receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | single protein format | Scientific Literature | ||
11. | ALA5135849 | B | Binding affinity to 5HT6 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | single protein format | Scientific Literature | ||
12. | ALA5135850 | B | Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | single protein format | Scientific Literature | ||
13. | ALA5135851 | B | Binding affinity to alpha2c (unknown origin) assessed as inhibition constant | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA5135854 | B | Binding affinity to beta1 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 2 | single protein format | Scientific Literature | ||
15. | ALA5135856 | B | Inhibition of D3 receptor (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
16. | ALA5135858 | B | Inhibition of D4 receptor (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
17. | ALA5135860 | B | Inhibition of SERT receptor (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
18. | ALA5135861 | B | Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 3 | single protein format | Scientific Literature | ||
19. | ALA5135863 | B | Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | single protein format | Scientific Literature | ||
20. | ALA5135864 | B | Binding affinity to 5HT2A receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | single protein format | Scientific Literature |