# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5126047 | B | Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | ALA5120960 | cell-based format | Scientific Literature | |
2. | ALA5126048 | B | Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | ALA5120960 | cell-based format | Scientific Literature | |
3. | ALA5126049 | B | Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | ALA5120960 | cell-based format | Scientific Literature | |
4. | ALA5126050 | B | Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | ALA5120960 | cell-based format | Scientific Literature | |
5. | ALA5126051 | B | Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | ALA5120960 | cell-based format | Scientific Literature | |
6. | ALA5126052 | B | Agonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | ALA5120960 | cell-based format | Scientific Literature | |
7. | ALA5126053 | B | Agonist activity at human P2X7R expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by YO-PRO-1 iodide addition and measured after 2 hrs by fluorescence based multimode plate reader analysis | Homo sapiens | 16 | ALA5120960 | cell-based format | Scientific Literature | |
8. | ALA5126054 | B | Antagonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 3 | ALA5120960 | cell-based format | Scientific Literature | |
9. | ALA5126055 | B | Antagonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 3 | ALA5120960 | cell-based format | Scientific Literature | |
10. | ALA5126056 | B | Antagonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 3 | ALA5120960 | cell-based format | Scientific Literature | |
11. | ALA5126057 | B | Antagonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 3 | ALA5120960 | cell-based format | Scientific Literature | |
12. | ALA5126058 | B | Antagonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 3 | ALA5120960 | cell-based format | Scientific Literature | |
13. | ALA5126059 | B | Antagonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 3 | ALA5120960 | cell-based format | Scientific Literature |