| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5100168 | B | Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic substrate incubated for 90 mins by microplate reader analysis | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 2. | ALA5100169 | B | Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Z-Lys(Ac)-AMC as fluorogenic substrate incubated for 90 mins by microplate reader analysis | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA5100170 | B | Selectivity index, ratio of IC50 for inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells to IC50 for inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 4. | ALA5100177 | F | Cytotoxicity against human HAL-01 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 5. | ALA5100178 | F | Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 6. | ALA5100179 | F | Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 19 | cell-based format | Scientific Literature |
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