| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5147131 | B | Displacement of [3H]epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membrane incubated for 3 hrs by scinitillation counting analysis | Homo sapiens | 6 | cell membrane format | Scientific Literature | ||
| 2. | ALA5147132 | B | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cell membrane incubated for 3 hrs by scinitillation counting analysis | Rattus norvegicus | 6 | cell membrane format | Scientific Literature | ||
| 3. | ALA5147134 | B | Selectivity ratio of Ki for rat alpha3beta4 nAChR expressed in HEK293 cell membrane to Ki for human alpha4beta2 nAChR expressed in HEK293 cell membrane | 3 | cell-based format | Scientific Literature | |||
| 4. | ALA5147135 | B | Partial agonist activity at high sensitivity isoform human (alpha4)2(beta2)3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at holding potential of -50 mV by two-electrode voltage clamp technique | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA5147136 | B | Partial agonist activity at low sensitivity isoform human (alpha4)3(beta2)2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at holding potential of -50 mV by two-electrode voltage clamp technique | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA5147137 | B | Partial agonist activity at high sensitivity isoform human (alpha4)2(beta2)3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at holding potential of -50 mV by two-electrode voltage clamp technique relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA5147138 | B | Partial agonist activity at low sensitivity isoform human (alpha4)3(beta2)2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at holding potential of -50 mV by two-electrode voltage clamp technique relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!