# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5106923 | B | Antagonist activity at human P2X1R transfected in CHO-K1 cells at 30 uM preincubated for 30 mins followed by alpha,beta-meATP addition by luminescence based assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
2. | ALA5106925 | B | Antagonist activity at human P2X2/3R transfected in CHO-K1 cells at 30 uM preincubated for 30 mins followed by alpha,beta-meATP addition by fluorescence based assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
3. | ALA5106927 | B | Antagonist activity at human P2X3R transfected in CHO-K1 cells at 30 uM preincubated for 30 mins followed by alpha,beta-meATP addition by fluorescence based assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
4. | ALA5106928 | B | Antagonist activity at human P2X4R transfected in HEK293 cells preincubated for 30 mins followed by CTP addition by fluorescence based assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
5. | ALA5106932 | B | Binding affinity to human D3 dopamine receptor at 10 uM relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA5106933 | B | Binding affinity to human 5HT2C serotonin receptor at 10 uM relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA5106938 | F | Neuroprotective activity in Wild type C57B/6 mouse model of middle cerebral artery occlusion assessed as reduction in hemispheric infract size at 5 mg/kg/day administered for 3 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA5106939 | F | Neuroprotective activity in Wild type C57B/6 mouse model of middle cerebral artery occlusion assessed as reduction in cortical infarct volume at 5 mg/kg/day administered for 3 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA5106940 | F | Neuroprotective activity in Wild type C57B/6 mouse model of middle cerebral artery occlusion assessed as reduction in striatal infarct volume at 5 mg/kg/day administered for 3 days | Mus musculus | 1 | organism-based format | Scientific Literature |