# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5134107 | F | Antiviral activity against Kunming mouse infected with Influenza A virus (A/Puerto Rico/8/1934(H1N1)) assessed as survival rate at 5 mg/kg, ip administered once a day for 5 days relative to control | Mus musculus | 2 | ALA5131467 | organism-based format | Scientific Literature | |
2. | ALA5134109 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in virus induced cytopathic effect pretreated with compound incubated for 1 hrs by MTT assay | Influenza A virus | 12 | ALA5131467 | organism-based format | Scientific Literature | |
3. | ALA5134110 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in virus induced cytopathic effect pre-treated with virus followed by cell infection for 1 hr by MTT assay | Influenza A virus | 15 | ALA5131467 | organism-based format | Scientific Literature | |
4. | ALA5134111 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in virus induced cytopathic effect during infection incubated for 1 hr by MTT assay | Influenza A virus | 12 | ALA5131467 | organism-based format | Scientific Literature | |
5. | ALA5134112 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in virus induced cytopathic effect after infection incubated for 1 hr by MTT assay | Influenza A virus | 10 | ALA5131467 | organism-based format | Scientific Literature | |
6. | ALA5134113 | T | Cytotoxicity against MDCK cells incubated for 1 hr by MTT assay | Canis lupus familiaris | 15 | ALA5131467 | cell-based format | Scientific Literature | |
7. | ALA5134114 | T | Cytotoxicity against MDCK cells by CCK-8 assay | Canis lupus familiaris | 5 | ALA5131467 | cell-based format | Scientific Literature | |
8. | ALA5134115 | T | Selectivity index, ratio of CC50 for MDCK cells to IC50 antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in virus induced cytopathic effect pre-treated with virus | 12 | ALA5131467 | cell-based format | Scientific Literature | ||
9. | ALA5134116 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in M1 mRNA level at 1 ug/ml measured after 24 hrs post infection by qRT-PCR analysis | Influenza A virus | 2 | ALA5131467 | organism-based format | Scientific Literature | |
10. | ALA5134117 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in HA mRNA level at 1 ug/ml measured after 24 hrs post infection by qRT-PCR analysis | Influenza A virus | 2 | ALA5131467 | organism-based format | Scientific Literature | |
11. | ALA5134118 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) NA-H374Y mutant infected in MDCK cells incubated for 1 hr by MTT assay | Influenza A virus | 3 | ALA5131467 | organism-based format | Scientific Literature | |
12. | ALA5134119 | F | Antiviral activity against Influenza A virus A/Aichi/2/68(H3N2) infected in MDCK cells incubated for 1 hr by MTT assay | Influenza A virus | 3 | ALA5131467 | organism-based format | Scientific Literature | |
13. | ALA5134120 | F | Antiviral activity against Influenza A virus A/FM/1/47 infected in MDCK cells incubated for 1 hr by MTT assay | Influenza A virus | 3 | ALA5131467 | organism-based format | Scientific Literature | |
14. | ALA5134121 | F | Antiviral activity against Influenza A virus 699(H3) clinical isolate infected in MDCK cells incubated for 1 hr by MTT assay | Influenza A virus | 3 | ALA5131467 | organism-based format | Scientific Literature | |
15. | ALA5134122 | F | Antiviral activity against Influenza B virus 699(H3) clinical isolate infected in MDCK cells incubated for 1 hr by MTT assay | Influenza B virus | 3 | ALA5131467 | organism-based format | Scientific Literature | |
16. | ALA5134125 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in viral nucleoprotein expression level at 2.5 ug/ml pre-treated with virus measured after 24 hrs post infection by indirect immunofluorescence assay | Influenza A virus | 1 | ALA5131467 | organism-based format | Scientific Literature | |
17. | ALA5134127 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in viral nucleoprotein expression level at 2.5 ug/ml pretreated with compound measured after 24 hrs post infection by indirect immunofluorescence assay | Influenza A virus | 1 | ALA5131467 | organism-based format | Scientific Literature | |
18. | ALA5134129 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as reduction in viral nucleoprotein expression level at 2.5 ug/ml during infection measured after 24 hrs post infection by indirect immunofluorescence assay | Influenza A virus | 1 | ALA5131467 | organism-based format | Scientific Literature | |
19. | ALA5134134 | F | Anti-inflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS induced TNF alpha level at 5 ug/ml by qRT-PCR analysis | Mus musculus | 1 | ALA5131467 | cell-based format | Scientific Literature | |
20. | ALA5134135 | F | Anti-inflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS induced IL-1 beta level at 5 ug/ml by qRT-PCR analysis | Mus musculus | 1 | ALA5131467 | cell-based format | Scientific Literature |