| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5141806 | B | Inhibition of N-terminal MBP-tagged full length human TPH1 assessed as reduction in 5-HTP formation incubated for 5 to 10 mins by fluorescence microplate reader analysis | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 2. | ALA5141807 | B | Inhibition of N-terminal MBP-tagged full length human TPH2 assessed as reduction in 5-HTP formation incubated for 5 to 10 mins by fluorescence microplate reader analysis | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 3. | ALA5141808 | P | Solubility of the compound in simulated intestinal fluid at upto 200 uM by HPLC-UV analysis | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA5141809 | P | Solubility of the compound in PBS at pH 7.4 at upto 200 uM by HPLC-UV analysis | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA5141810 | P | Solubility of the compound in simulated gastric fluid at upto 200 uM by HPLC-UV analysis | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA5141811 | A | Metabolic stability in rat hepatocytes assessed as intrinsic clearance | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 7. | ALA5141812 | A | Plasma protein binding in human | Homo sapiens | 14 | cell-free format | Scientific Literature | ||
| 8. | ALA5141813 | A | Plasma protein binding in rat | Rattus norvegicus | 14 | cell-free format | Scientific Literature | ||
| 9. | ALA5141814 | A | Apparent permeability across apical to basolateral side in human Caco-2 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 10. | ALA5141815 | A | Apparent permeability across basolateral to apical side in human Caco-2 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 11. | ALA5141816 | A | Metabolic stability in human hepatocytes assessed as half life | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 12. | ALA5141817 | A | Metabolic stability in rat hepatocytes assessed as half life | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 13. | ALA5141818 | A | Metabolic stability in human hepatocytes assessed as intrinsic clearance | Homo sapiens | 14 | cell-based format | Scientific Literature |
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