| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5131349 | T | Effect on angiogenic activity in 24 hrs post-fertilized fil1/EGFP transgenic zebrafish embryo assessed as subintestinal vessel area at 100 nM measured after 48 hrs by fluorescence microscopy (Rvb = 100%) | Danio rerio | 8 | assay format | Scientific Literature | ||
| 2. | ALA5131351 | B | Inhibition of c-Myb (unknown origin) expressed in HEK293T cells measured after 16 hrs by steady-glo luciferase reporter gene assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 3. | ALA5131352 | T | Cytotoxicity against human EA.hy 926 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA5131353 | F | Cytotoxicity against human 518A2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA5131354 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA5131355 | F | Cytotoxicity against p53-deficient human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA5131356 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA5131357 | F | Cytotoxicity against human multidrug-resistant KB-V1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA5131358 | F | Cytotoxicity against human multidrug-resistant KB-V1 cells assessed as reduction in cell viability measured after 72 hrs in presence of verapamil by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA5131359 | F | Cytotoxicity against human U-87 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA5131360 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 12. | ALA5131361 | T | Cytotoxicity against HDFa cells assessed as reduction in cell viability at 0.0005 to 100 uM measured after 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA5131362 | B | Inhibition of porcine brain tubulin polymerization at 5 uM measured at 10 mins interval for 100 mins by turbidimetric assay | Sus scrofa | 8 | tissue-based format | Scientific Literature | ||
| 14. | ALA5131363 | B | Induction of microtubule fragmentation in human 518A2 cells at 25 nM measured after 24 hrs by immunofluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA5131364 | B | Induction of microtubule fragmentation in human 518A2 cells assessed as appearance of area with dorsal stress fibre at 25 nM measured after 24 hrs by immunofluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 16. | ALA5131365 | B | Induction of microtubule fragmentation in human 518A2 cells assessed as appearance of area with transverse arcs at 25 nM measured after 24 hrs by immunofluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 17. | ALA5131367 | F | Cell cycle arrest in human 5182A cells assessed as increase in accumulation at sub-G1 phase at 25 nM measured after 6 to 24 hrs by propidium iodide staining based FACS analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA5131368 | F | Cell cycle arrest in human 5182A cells assessed as increase in accumulation at G2/M phase at 25 nM measured after 6 to 24 hrs by propidium iodide staining based FACS analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 19. | ALA5131370 | B | Activation of caspase-3/7 activity in human 518A2 cells at 25 nM preincubated for 24 hrs followed by caspase-3/7 fluorogenic substrate addition and measured after 60 mins by fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 20. | ALA5131374 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature |
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