# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5120693 | B | Inhibition of HIF-1alpha (unknown origin) transcriptional activity expressed in HEK293T cells co-transfected with renilla and HRE-firelfly luciferase incubated for 24 hrs by dual luciferase reporter gene assay | Homo sapiens | 22 | ALA5113556 | cell-based format | Scientific Literature | |
2. | ALA5120694 | T | Cytotoxicity against HEK293T cells at 50 uM | Homo sapiens | 27 | ALA5113556 | cell-based format | Scientific Literature | |
3. | ALA5120695 | F | Downregulation of VEGF mRNA expression in HEK293T cells measured after 24 hrs under hypoxia condition by Western blot analysis | Homo sapiens | 2 | ALA5113556 | cell-based format | Scientific Literature | |
4. | ALA5120696 | F | Downregulation of PDK1 mRNA expression in HEK293T cells measured after 24 hrs under hypoxia condition by Western blot analysis | Homo sapiens | 2 | ALA5113556 | cell-based format | Scientific Literature | |
5. | ALA5120697 | F | Downregulation of VEGF mRNA expression in HEK293T cells at 0.01 to 50 uM measured after 24 hrs under normoxia condition by Western blot analysis | Homo sapiens | 2 | ALA5113556 | cell-based format | Scientific Literature | |
6. | ALA5120698 | F | Downregulation of PDK1 mRNA expression in HEK293T cells at 0.01 to 50 uM measured after 24 hrs under normoxia condition by Western blot analysis | Homo sapiens | 2 | ALA5113556 | cell-based format | Scientific Literature | |
7. | ALA5120699 | F | Downregulation of VEGF protein expression in HEK293T cells at 50 uM measured after 24 hrs under normoxia condition by Western blot analysis relative to control | Homo sapiens | 1 | ALA5113556 | cell-based format | Scientific Literature | |
8. | ALA5120700 | F | Effect on HIF-1alpha protein expression in HEK293T cells at 2 to 10 uM under hypoxia condition by Western blot analysis | Homo sapiens | 2 | ALA5113556 | cell-based format | Scientific Literature |