# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5158466 | B | Inhibition of recombinant human liver Cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by fluorescence assay | Homo sapiens | 10 | ALA5154724 | assay format | Scientific Literature | |
2. | ALA5158467 | B | Inhibition of Cathepsin E (unknown origin) using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by fluorescence assay | Homo sapiens | 9 | ALA5154724 | single protein format | Scientific Literature | |
3. | ALA5158468 | B | Inhibition of BACE1 (unknown origin) using Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2 as substrate incubated for 120 mins by fluorescence assay | Homo sapiens | 8 | ALA5154724 | single protein format | Scientific Literature | |
4. | ALA5158469 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 5 | ALA5154724 | cell-based format | Scientific Literature | |
5. | ALA5158470 | F | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 5 | ALA5154724 | cell-based format | Scientific Literature | |
6. | ALA5158471 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 5 | ALA5154724 | cell-based format | Scientific Literature | |
7. | ALA5158472 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability at 10 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 5 | ALA5154724 | cell-based format | Scientific Literature | |
8. | ALA5158476 | A | Drug uptake in human MDA-MB-231 cells assessed as increase in internalization at 10 uM after 16 to 24 hrs by LTG/Hoechst 33258 staining based confocal laser scanning microscopy | Homo sapiens | 2 | ALA5154724 | cell-based format | Scientific Literature |