| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5160539 | F | Antiproliferative activity against human U2OS cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA5154776 | cell-based format | Scientific Literature | |
| 2. | ALA5160540 | A | Inhibition of CYP2C19 in rat liver microsomes at 100 uM using voriconazole as substrate preincubated for 5 min followed by NADPH addition and measured after 40 mins by UHPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA5154776 | microsome format | Scientific Literature | |
| 3. | ALA5160543 | F | Antiproliferative activity against human MG-63 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA5154776 | cell-based format | Scientific Literature | |
| 4. | ALA5160546 | F | Antiproliferative activity against human MNNG/HOS cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA5154776 | cell-based format | Scientific Literature | |
| 5. | ALA5160547 | F | Antiproliferative activity against human SAOS-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA5154776 | cell-based format | Scientific Literature | |
| 6. | ALA5160548 | B | Inhibition of PDGFRbeta phosphorylation in human MNNG/HOS cells incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 7. | ALA5160549 | F | Inhibition of colony formation in human MNNG/HOS cells by crystal violet staining based analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 8. | ALA5160550 | B | Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assay | Homo sapiens | 14 | ALA5154776 | single protein format | Scientific Literature | |
| 9. | ALA5160551 | B | Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assay | Homo sapiens | 14 | ALA5154776 | single protein format | Scientific Literature | |
| 10. | ALA5160552 | F | Induction of cell cycle arrest in human MNNG/HOS cells assessed as accumulation of cells at G2/M phase incubated for 48 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 11. | ALA5160553 | F | Induction of cell cycle arrest in human MG-63 cells assessed as accumulation of cells at G0/G1 phase incubated for 48 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 12. | ALA5160556 | F | Inhibition of alpha tubulin expression in human MNNG/HOS cells assessed as effect on microtubule network at 0.1 to 0.4 uM by DAPI staining based immunofluorescence microscopic analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 13. | ALA5160557 | F | Inhibition of alpha tubulin expression in human MG-63 cells assessed as effect on microtubule network at 0.1 to 0.4 uM by DAPI staining based immunofluorescence microscopic analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 14. | ALA5160558 | F | Induction of apoptosis in human MNNG/HOS cells at 0.4 uM after 48 hrs by Annexin V/PI staining based flow cytometric analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 15. | ALA5160559 | F | Induction of apoptosis in human MG-63 cells at 0.4 uM after 48 hrs by Annexin V/PI staining based flow cytometric analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 16. | ALA5160560 | F | Inhibition of PDGF AA/BB-stimulated human MNNG/HOS cell proliferation measured after 48 hrs by MTT assay | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 17. | ALA5160561 | F | Inhibition of PDGF AA/BB-stimulated human MG-63 cell proliferation measured after 48 hrs by MTT assay | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 18. | ALA5160562 | F | Induction of DNA damage in human MNNG/HOS cells assessed as tail DNA at 0.1 to 0.4 uM measured after 48 hrs by comet assay | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 19. | ALA5160563 | F | Induction of DNA damage in human MG-63 cells assessed as tail DNA at 0.1 to 0.4 uM measured after 48 hrs by comet assay | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature | |
| 20. | ALA5160564 | B | Inhibition of PDGFRbeta-mediated downstream signalling in human MG-63 cells assessed as suppression of STAT3 phosphorylation at 0.1 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5154776 | cell-based format | Scientific Literature |
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