# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5126194 | F | Antagonist activity at LPA1 receptor (unknown origin) expressed in cells assessed as blockade of LPA-induced calcium mobilization at 10 uM measured after 120 secs by Fluo-4 NW dye based assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
2. | ALA5126195 | F | Antagonist activity at LPA2 receptor (unknown origin) expressed in cells assessed as blockade of LPA-induced calcium mobilization measured after 120 secs by Fluo-4 NW dye based assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA5126196 | F | Antagonist activity at LPA2 receptor (unknown origin) expressed in cells assessed as maximal blockade of LPA-induced calcium mobilization at 10 uM measured after 120 secs by Fluo-4 NW dye based assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
4. | ALA5126199 | F | Antagonist activity at LPA3 receptor (unknown origin) expressed in cells assessed as blockade of LPA-induced calcium mobilization at 10 uM measured after 120 secs by Fluo-4 NW dye based assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
5. | ALA5126200 | F | Agonist activity at LPA2 receptor (unknown origin) expressed in cells assessed as calcium mobilization at 10 uM by Fluo-4 NW dye based assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
6. | ALA5126205 | A | Metabolic stability in CD1 mouse liver microsomes assessed as half life by HPLC-MS analysis | Mus musculus | 2 | microsome format | Scientific Literature | ||
7. | ALA5126206 | A | Metabolic stability in human liver microsomes assessed as half life by HPLC-MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
8. | ALA5126207 | A | Permeability of the compound by PAMPA | 2 | assay format | Scientific Literature |