# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5115453 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in colony formation incubated for 14 days by cresyl-violet staining based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA5115454 | B | Inhibition of SRPK1 (unknown origin) at 0.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA5115455 | B | Inhibition of PAK1 (unknown origin) at 0.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA5115456 | B | Inhibition of EGFR (unknown origin) at 0.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA5115457 | B | Inhibition of IGF1R (unknown origin) at 0.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA5115458 | B | Inhibition of recombinant human PLK4 incubated for 60 mins by Lanthascreen Eu kinase binding assay | Homo sapiens | 43 | single protein format | Scientific Literature | ||
7. | ALA5115459 | B | Inhibition of PAK4 (unknown origin) incubated for 60 mins by time-resolved HTRF assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
8. | ALA5115460 | B | Selectivity index, ratio of IC50 for inhibition of PAK4 (unknown origin) by time-resolved HTRF assay to IC50 for inhibition of recombinant human PLK4 by Lanthascreen Eu kinase binding assay | Homo sapiens | 26 | assay format | Scientific Literature | ||
9. | ALA5115461 | F | Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 5 days by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
10. | ALA5115462 | F | Antiproliferative activity against human BT-474 cells assessed as cell growth inhibition incubated for 5 days by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
11. | ALA5115463 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 5 days by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
12. | ALA5115464 | A | Plasma stability in human assessed as compound remaining at 100 uM measured after 10 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
13. | ALA5115465 | A | Plasma stability in human assessed as compound remaining at 100 uM measured after 30 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
14. | ALA5115466 | A | Plasma stability in human assessed as compound remaining at 100 uM measured after 60 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
15. | ALA5115467 | A | Plasma stability in human assessed as compound remaining at 100 uM measured after 120 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
16. | ALA5115468 | A | Plasma stability in human assessed as half-life at 100 uM measured upto 120 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
17. | ALA5115469 | A | Metabolic stability in human liver microsomes assessed as half-life at 100 uM measured upto 60 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
18. | ALA5115470 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 100 uM measured upto 60 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
19. | ALA5115471 | A | Metabolic stability in human liver as intrinsic clearance at 100 uM measured upto 60 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
20. | ALA5115472 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 100 uM measured after 60 mins in the presence of NADPH by LC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature |