# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5104257 | F | Cytotoxicity against human Ca9-22 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA5104258 | F | Cytotoxicity against human HSC-2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
3. | ALA5104265 | B | Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 75 | single protein format | Scientific Literature | ||
4. | ALA5104267 | B | Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 46 | single protein format | Scientific Literature | ||
5. | ALA5104268 | B | Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 77 | single protein format | Scientific Literature | ||
6. | ALA5104269 | T | Selectivity index, ratio of CC50 for cytotoxicity against HGF cells to CC50 for cytotoxicity against human Ca9-22 cells by MTT method | 14 | cell-based format | Scientific Literature | |||
7. | ALA5104270 | T | Selectivity index, ratio of CC50 for cytotoxicity against HPLF cells to CC50 for cytotoxicity against human Ca9-22 cells by MTT method | 14 | cell-based format | Scientific Literature | |||
8. | ALA5104271 | T | Selectivity index, ratio of CC50 for cytotoxicity against HGF cells to CC50 for cytotoxicity against human HSC-2 cells by MTT method | 14 | cell-based format | Scientific Literature | |||
9. | ALA5104272 | T | Selectivity index, ratio of CC50 for cytotoxicity against HPLF cells to CC50 for cytotoxicity against human HSC-2 cells by MTT method | 14 | cell-based format | Scientific Literature | |||
10. | ALA5104273 | B | Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 48 | single protein format | Scientific Literature | ||
11. | ALA5104274 | B | Selectivity ratio of Ki for human recombinant CA1 to Ki for human recombinant CA9 by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
12. | ALA5104275 | B | Selectivity ratio of Ki for human recombinant CA2 to Ki for human recombinant CA9 by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
13. | ALA5242691 | F | Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA5242692 | F | Cytotoxicity against human HSC-2 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5242693 | B | Inhibition of human CA1 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
16. | ALA5242694 | B | Inhibition of human CA2 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
17. | ALA5242695 | B | Inhibition of human CA9 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
18. | ALA5242696 | B | Inhibition of human CA12 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
19. | ALA5242697 | B | Selectivity index, ratio of Ki for inhibition of human CA1 to Ki for inhibition of human CA9 | Homo sapiens | 1 | assay format | Scientific Literature | ||
20. | ALA5242698 | B | Selectivity index, ratio of Ki for inhibition of human CA2 to Ki for inhibition of human CA9 | Homo sapiens | 1 | assay format | Scientific Literature |