# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA692692 | Binding | Inhibitory activity against histone deacetylase enzyme derived from partially purified extracts of Eimeria tenella protozoa using [3H]11 as radioligand | Cryptosporidium parvum | 23 | ALA1133988 | single protein format | Scientific Literature | |
2. | ALA692694 | Binding | Binding affinity towards HDAC enzyme derived from Eimeria tenella protozoa | Eimeria tenella | 11 | ALA1133988 | single protein format | Scientific Literature | |
3. | ALA880154 | Binding | Binding affinity towards HDAC enzyme derived from chicken liver (CL) cells | Gallus gallus | 11 | ALA1133988 | assay format | Scientific Literature | |
4. | ALA857631 | Binding | Inhibitory activity against histone deacetylase (HDAC) enzyme derived from partially purified extracts of human HeLa cells using [3H]11 as radioligand | Homo sapiens | 17 | ALA1133988 | cell-based format | Scientific Literature | |
5. | ALA692715 | Functional | Tested for mammalian cell (HeLa)-based antiproliferative assay | Homo sapiens | 11 | ALA1133119 | cell-based format | Scientific Literature | |
6. | ALA691505 | Binding | Tested for Histone deacetylase enzyme inhibition assay using Eimeria tenella extract | Eimeria tenella | 5 | ALA1133119 | single protein format | Scientific Literature | |
7. | ALA691506 | Binding | Displacement of [3H]-Apicidin A from Histone deacetylase of Eimeria tenella extract | Eimeria tenella | 13 | ALA1133119 | single protein format | Scientific Literature | |
8. | ALA691509 | Binding | Inhibitory concentration determined against Histone deacetylase from Eimeria tenella | Eimeria tenella | 6 | ALA1145900 | single protein format | Scientific Literature | |
9. | ALA694955 | Binding | Inhibition of [3H]-Apicidin A binding to Histone deacetylase of chick liver extract | Gallus gallus | 13 | ALA1133119 | assay format | Scientific Literature | |
10. | ALA693169 | Binding | Tested for Histone deacetylase enzyme inhibition assay using mammalian cell nuclear extract (HeLa) | Homo sapiens | 5 | ALA1133119 | protein format | Scientific Literature | |
11. | ALA695144 | Binding | Inhibitory concentration against human Histone deacetylase in Hela cells | Homo sapiens | 10 | ALA1145900 | cell-based format | Scientific Literature | |
12. | ALA700722 | Functional | Cytotoxicity tested against KB cells of human nasopharyngeal epithelial cell line | Homo sapiens | 4 | ALA1134828 | cell-based format | Scientific Literature | |
13. | ALA703313 | Functional | Effective dose required for antiprotozoal activity against Leishmania donovani; T: Toxicity to both mouse macrophage host cells and intracellular parasites prevented determination of antiprotozoal activity | Leishmania donovani | 1 | ALA1134828 | organism-based format | Scientific Literature | |
14. | ALA713277 | Functional | In vitro antiprotozoal activity using Mauden-Downing bovine kidney host cells infected with Eimeria tenella | Eimeria tenella | 29 | ALA1133988 | organism-based format | Scientific Literature | |
15. | ALA721487 | Functional | Inhibitory concentration against Plasmodium falciparum in mice (Mus musculus) | Plasmodium falciparum | 10 | ALA1145900 | organism-based format | Scientific Literature | |
16. | ALA1637552 | Functional | Antimalarial activity against Plasmodium falciparum infected mouse assessed as reduction in parasitemia at 50 mg/kg, ip | Plasmodium falciparum | 1 | ALA1629555 | organism-based format | Scientific Literature | |
17. | ALA1637553 | Functional | Antimicrobial activity against Plasmodium falciparum | Plasmodium falciparum | 1 | ALA1629555 | organism-based format | Scientific Literature | |
18. | ALA1049810 | Binding | Inhibition of HDAC6 in human Jurkat cells assessed as acetylated alpha-tubulin level at 2 uM after 24 hrs by Western blotting | Homo sapiens | 1 | ALA1156016 | cell-based format | Scientific Literature | |
19. | ALA1049811 | Binding | Inhibition of class 1 HDAC in human Jurkat cells assessed as acetylated histone H3 level at 2 uM after 24 hrs by Western blotting | Homo sapiens | 1 | ALA1156016 | cell-based format | Scientific Literature | |
20. | ALA1049812 | Binding | Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorimetric assay | Homo sapiens | 29 | ALA1156016 | cell-based format | Scientific Literature |