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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5163405 A Ratio of drug concentration in rat blood to plasma at 20 mg/kg, po measured after 2 hrs Rattus norvegicus 1 ALA5154828 organism-based format Scientific Literature 2. ALA5163406 F Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 6 days by cell titre glo luminescence assay Homo sapiens 60 ALA5154828 cell-based format Scientific Literature 3. ALA5163407 B Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysis Homo sapiens 50 ALA5154828 cell-based format Scientific Literature 4. ALA5163408 B Induction of ERalpha degradation in human MCF7 cells assessed as maximum degradation incubated for 24 hrs by Western blot analysis relative to control Homo sapiens 50 ALA5154828 cell-based format Scientific Literature 5. ALA5163411 B Antagonist activity at ERbeta expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of di-arylpropionitrile by luciferase reporter gene assay Homo sapiens 8 ALA5154828 cell-based format Scientific Literature 6. ALA5163413 A Cmax in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Rattus norvegicus 7 ALA5154828 organism-based format Scientific Literature 7. ALA5163415 A AUC (0 to t) in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Rattus norvegicus 7 ALA5154828 organism-based format Scientific Literature 8. ALA5163416 A Elimination half life in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Rattus norvegicus 1 ALA5154828 organism-based format Scientific Literature 9. ALA5163417 A Elimination half life in ICR mouse at 2 mg/kg, iv measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 10. ALA5163418 A Elimination half life in ICR mouse at 5 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 11. ALA5163419 A Tmax in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Rattus norvegicus 1 ALA5154828 organism-based format Scientific Literature 12. ALA5163420 A Tmax in ICR mouse at 5 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 13. ALA5163421 A Cmax in ICR mouse at 2 mg/kg, iv measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 14. ALA5163422 A Cmax in ICR mouse at 5 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 15. ALA5163423 A AUC (0 to t) in ICR mouse at 5 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 16. ALA5163424 A AUC (0 to t) in ICR mouse at 2 mg/kg, iv measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 17. ALA5163425 A MRT in ICR mouse at 5 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 18. ALA5163426 A MRT in ICR mouse at 2 mg/kg, iv measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature 19. ALA5163427 A MRT in Sprague-Dawley rat at 10 mg/kg, po measured up to 24 hrs by LC/MS/MS analysis Rattus norvegicus 1 ALA5154828 organism-based format Scientific Literature 20. ALA5163428 A Clearance in ICR mouse at 2 mg/kg, iv measured up to 24 hrs by LC/MS/MS analysis Mus musculus 1 ALA5154828 organism-based format Scientific Literature