# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5151419 | A | Permeability in PBS buffer measured after 18 hrs by PAMPA based LC-MS analysis | 6 | ALA5149989 | assay format | Scientific Literature | ||
2. | ALA5151420 | A | Effective permeability in PBS buffer assessed as mass retention measured after 18 hrs by PAMPA based LC-MS analysis | 5 | ALA5149989 | assay format | Scientific Literature | ||
3. | ALA5151421 | A | Permeability across apical to basal side in human Caco-2 cells measured at 0.5 to 2 hrs by LC-MS analysis | Homo sapiens | 7 | ALA5149989 | cell-based format | Scientific Literature | |
4. | ALA5151422 | A | Permeability across apical to basal side in human Caco-2 cells assessed as drug recovery measured at 0.5 to 2 hrs by LC-MS analysis relative to control | Homo sapiens | 7 | ALA5149989 | cell-based format | Scientific Literature | |
5. | ALA5151423 | A | Permeability across basal to apical side in human Caco-2 cells measured at 0.5 to 2 hrs by LC-MS analysis | Homo sapiens | 7 | ALA5149989 | cell-based format | Scientific Literature | |
6. | ALA5151424 | A | Permeability across basal to apical side in human Caco-2 cells assessed as drug recovery measured at 0.5 to 2 hrs by LC-MS analysis relative to control | Homo sapiens | 7 | ALA5149989 | cell-based format | Scientific Literature | |
7. | ALA5151425 | A | Efflux ratio of permeability from apical to basolateral side over basolateral to apical side in human Caco2 cells measured at 0.5 to 2 hrs by LC-MS analysis | Homo sapiens | 7 | ALA5149989 | cell-based format | Scientific Literature | |
8. | ALA5151426 | A | Permeability across apical to basal side in human Caco-2 cells preincubated with verapamil for 30 mins followed by compound addition measured at 0.5 to 2 hrs by LC-MS analysis | Homo sapiens | 7 | ALA5149989 | cell-based format | Scientific Literature | |
9. | ALA5151427 | A | Permeability across apical to basal side in human Caco-2 cells assessed as drug recovery preincubated with verapamil for 30 mins followed by compound addition measured at 0.5 to 2 hrs by LC-MS analysis relative to control | Homo sapiens | 7 | ALA5149989 | cell-based format | Scientific Literature | |
10. | ALA5151442 | B | Binding affinity to CypA (unknown origin) assessed as inhibition constant by isomer specific proteolysis assay | Homo sapiens | 5 | ALA5149989 | single protein format | Scientific Literature |