# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5146441 | B | Inhibition of recombinant human HDAC1 using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assay | Homo sapiens | 21 | ALA5143616 | single protein format | Scientific Literature | |
2. | ALA5146442 | B | Inhibition of recombinant human HDAC6 using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assay | Homo sapiens | 21 | ALA5143616 | single protein format | Scientific Literature | |
3. | ALA5146443 | B | Inhibition of HDAC2 (unknown origin) using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assay | Homo sapiens | 2 | ALA5143616 | single protein format | Scientific Literature | |
4. | ALA5146444 | B | Inhibition of HDAC3 (unknown origin) | Homo sapiens | 2 | ALA5143616 | single protein format | Scientific Literature | |
5. | ALA5146445 | B | Inhibition of HDAC8 (unknown origin) using Boc-Lys-(triflouroacetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assay | Homo sapiens | 2 | ALA5143616 | single protein format | Scientific Literature | |
6. | ALA5146446 | F | Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay | Mus musculus | 20 | ALA5143616 | cell-based format | Scientific Literature | |
7. | ALA5146447 | F | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay | Homo sapiens | 20 | ALA5143616 | cell-based format | Scientific Literature | |
8. | ALA5146448 | F | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 20 | ALA5143616 | cell-based format | Scientific Literature | |
9. | ALA5146449 | F | Antiproliferative activity against mouse CT26 cells after 72 hrs by MTT assay | Mus musculus | 20 | ALA5143616 | cell-based format | Scientific Literature | |
10. | ALA5146450 | B | Inhibition of HDAC6 in mouse B16 cells assessed as accumulation of acetylated alpha-tubulin level after 24 hrs by Western blotting analysis | Mus musculus | 4 | ALA5143616 | cell-based format | Scientific Literature | |
11. | ALA5146451 | B | Inhibition of HDAC6 in mouse B16 cells assessed as accumulation of acetylated alpha-tubulin level at 6 uM after 2 to 12 hrs by Western blotting analysis | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
12. | ALA5146452 | B | Inhibition of HDAC6 in mouse B16 cells assessed as accumulation of acetylated alpha-tubulin level at 2 to 6 uM after 24 hrs by Western blotting analysis | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
13. | ALA5146453 | B | Inhibition of HDAC6 in mouse CT26 cells assessed as accumulation of acetylated alpha-tubulin level at 6 uM after 2 to 24 hrs by Western blotting analysis | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
14. | ALA5146454 | B | Inhibition of HDAC6 in mouse CT26 cells assessed as accumulation of acetylated alpha-tubulin level at 2 to 6 uM after 24 hrs by Western blotting analysis | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
15. | ALA5146456 | B | Inhibition of HDAC1 in mouse B16 cells assessed as accumulation of acetylated H3 level at 2 to 6 uM after 24 hrs by Western blotting analysis | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
16. | ALA5146458 | B | Inhibition of HDAC1 in mouse CT26 cells assessed as accumulation of acetylated H3 level at 2 to 6 uM after 24 hrs by Western blotting analysis | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
17. | ALA5146459 | F | Inhibition of migration of mouse B16 cells at 0.2 to 1 uM measured after 6 to 12 hrs by wound healing assay | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
18. | ALA5146460 | F | Inhibition of migration of mouse CT26 cells at 0.2 to 1 uM measured after 6 to 12 hrs by wound healing assay | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
19. | ALA5146461 | F | Induction of apoptosis in mouse B16 cells assessed as apoptotic cells at 8 uM measured by Annexin V-FITC/PI staining based flow cytometry method | Mus musculus | 1 | ALA5143616 | cell-based format | Scientific Literature | |
20. | ALA5146462 | F | Induction of apoptosis in mouse CT26 cells assessed as apoptotic cells at 6 uM measured by Annexin V-FITC/PI staining based flow cytometry method | Mus musculus | 2 | ALA5143616 | cell-based format | Scientific Literature |