# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5135900 | T | Cytotoxicity against HEL 299 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
2. | ALA5135901 | F | Antiviral activity against SARS-CoV-2 infected in eGFP expressing African green monkey Vero E6 cells assessed as reduction in virus-induced cytopathic effect measured after 4 days post infection by laser scanning microscopic analysis | Severe acute respiratory syndrome coronavirus 2 | 42 | organism-based format | Scientific Literature | ||
3. | ALA5135902 | T | Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay | Chlorocebus sabaeus | 29 | cell-based format | Scientific Literature | ||
4. | ALA5135903 | T | Selectivity index, ratio of CC50 for cytotoxicity against African green monkey Vero E6 cells to EC50 for antiviral activity against SARS-CoV-2 infected in eGFP expressing African green monkey Vero E6 cells | 18 | cell-based format | Scientific Literature | |||
5. | ALA5135904 | F | Antiviral activity against HCoV-229E infected in HEL 299 cells assessed as reduction in virus-induced cytopathic effect preincubated with compound followed by viral infection and measured after 7 days by MTS cell viability assay | Human coronavirus 229E | 14 | organism-based format | Scientific Literature | ||
6. | ALA5135905 | T | Selectivity index, ratio of CC50 for cytotoxicity against HEL 299 cells to EC50 for antiviral activity against HCoV-229E infected in HEL 299 cells | 14 | cell-based format | Scientific Literature | |||
7. | ALA5135906 | F | Antiviral activity against HCoV-OC43 infected in HEL 299 cells assessed as reduction in virus-induced cytopathic effect preincubated with compound followed by viral infection and measured after 7 days by MTS cell viability assay | Human coronavirus OC43 | 14 | cell-based format | Scientific Literature | ||
8. | ALA5135907 | T | Selectivity index, ratio of CC50 for cytotoxicity against HEL 299 cells to EC50 for antiviral activity against HCoV-OC43 infected in HEL 299 cells | 14 | cell-based format | Scientific Literature |