# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5106177 | B | Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhibition of PGE2 production after 30 mins by enzyme immuno-assay (EIA) | Mus musculus | 19 | cell-based format | Scientific Literature | ||
2. | ALA5106178 | B | Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA) | Mus musculus | 19 | cell-based format | Scientific Literature | ||
3. | ALA5106179 | B | Ratio IC50 for inhibition of COX1 in mouse J774 cells over inhibition of COX2 in mouse J774 cells | Mus musculus | 19 | cell-based format | Scientific Literature | ||
4. | ALA5106184 | F | Vasorelaxant activity in Sprague-Dawley rat aortic rings assessed as reduction in L-phenylephrine-induced contractions at 0.01 to 100 uM relative to control | Rattus norvegicus | 6 | tissue-based format | Scientific Literature | ||
5. | ALA5106185 | F | Vasorelaxant activity in Sprague-Dawley rat aortic rings assessed as reduction in L-phenylephrine-induced contractions at 0.01 to 100 uM in presence of 10 uM guanylate cyclase inhibitor ODQ relative to control | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
6. | ALA5106186 | F | Analgesic activity against acetic acid-induced male CD1 albino mouse model assessed as number of writhes at 10 mg/kg, po measured after 30 mins by abdominal constriction test | Mus musculus | 6 | organism-based format | Scientific Literature | ||
7. | ALA5106187 | F | Analgesic activity against acetic acid-induced male CD1 albino mouse model assessed as number of writhes at 20 mg/kg, po measured after 30 mins by abdominal constriction test | Mus musculus | 6 | organism-based format | Scientific Literature | ||
8. | ALA5106188 | F | Analgesic activity against acetic acid-induced male CD1 albino mouse model assessed as number of writhes at 30 mg/kg, po measured after 30 mins by abdominal constriction test | Mus musculus | 6 | organism-based format | Scientific Literature | ||
9. | ALA5106189 | F | Anti-hyperalgesic activity in carrageenan-induced hyperalgesia male Sprague-Dawley rat model assessed as paw withdrawal threshold at 20 mg/kg, po measured 15 mins after compound administration by paw pressure test | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
10. | ALA5106190 | F | Anti-hyperalgesic activity in carrageenan-induced hyperalgesia male Sprague-Dawley rat model assessed as paw withdrawal threshold at 20 mg/kg, po measured 30 mins after compound administration by paw pressure test | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
11. | ALA5106191 | F | Anti-hyperalgesic activity in carrageenan-induced hyperalgesia male Sprague-Dawley rat model assessed as paw withdrawal threshold at 20 mg/kg, po measured 45 mins after compound administration by paw pressure test | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
12. | ALA5106192 | F | Anti-hyperalgesic activity in carrageenan-induced hyperalgesia male Sprague-Dawley rat model assessed as paw withdrawal threshold at 20 mg/kg, po measured 60 mins after compound administration by paw pressure test | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
13. | ALA5106197 | F | Anti-hyperalgesic activity in carrageenan-induced hyperalgesia male Sprague-Dawley rat model assessed as paw edema volume at 20 mg/kg, po measured 30 mins after compound administration by plethysmometer analysis | Rattus norvegicus | 6 | organism-based format | Scientific Literature |