# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5112264 | B | Competitive binding affinity to recombinant Pseudomonas aeruginosa LecA expressed in Escherichia coli BL21(DE3) incubated for 30 to 60 mins by fluorescent polarization assay | Pseudomonas aeruginosa | 5 | assay format | Scientific Literature | ||
2. | ALA5112268 | A | Prodrug activation assessed as LasB-mediated drug release in Pseudomonas aeruginosa PA14 cell supernatant in presence of human blood plasma and measured for 3 hrs by HPLC-MS analysis | Pseudomonas aeruginosa | 6 | cell-free format | Scientific Literature | ||
3. | ALA5112269 | A | Stability of compound in human blood plasma spiked with Pseudomonas aeruginosa PA14 matrix assessed as hydrolysis of prodrug and measured upto 3 hrs by HPLC-MS/MS analysis | Homo sapiens | 6 | cell-free format | Scientific Literature | ||
4. | ALA5112270 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 10 mins in PBS buffer followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
5. | ALA5112271 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 3 hrs in PBS buffer followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
6. | ALA5112272 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 10 mins in matrix containing human blood plasma spiked with Pseudomonas aeruginosa cell culture supernatant in PBS buffer followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
7. | ALA5112273 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 3 hrs in matrix containing 50% human blood plasma and 10% Pseudomonas aeruginosa cell culture supernatant in PBS followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
8. | ALA5112274 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 3 hrs in matrix containing human blood plasma spiked with Pseudomonas aeruginosa cell culture supernatant in PBS buffer followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
9. | ALA5112275 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 3 hrs in matrix containing Pseudomonas aeruginosa cell culture supernatant in PBS buffer followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
10. | ALA5112276 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 10 mins in matrix containing human blood plasma spiked with fresh LB medium in PBS followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
11. | ALA5112277 | F | Antibacterial activity against Pseudomonas aeruginosa PA14 assessed inhibition of bacterial growth preincubated for 3 hrs in matrix containing human blood plasma spiked with fresh LB medium in PBS followed by overnight grown bacterial culture addition incubated for 18 to 20 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature |