| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5124717 | B | Binding affinity to N-terminal His6/Sumo-tagged NSD2 PWWP1 domain (211 to 350 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using ATKAARKSAPATGGV-Lys (me)2-KPHRYRPG polypeptide as substrate incubated for 3 hrs by HTRF assay | Homo sapiens | 38 | ALA5120900 | assay format | Scientific Literature | |
| 2. | ALA5124718 | B | Binding affinity to His6/Sumo-tagged NSD2 PWWP1 (unknown origin) (208 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as increase in melting temperature by thermal shift assay | Homo sapiens | 1 | ALA5120900 | assay format | Scientific Literature | |
| 3. | ALA5124719 | B | Inhibition of NSD2 (unknown origin) assessed as effect on H3K36me2 level using histone H3 as substrate incubated for 20 mins by AlphaLISA method | Homo sapiens | 1 | ALA5120900 | single protein format | Scientific Literature | |
| 4. | ALA5124720 | B | Inhibition of NSD2 in human RS4-11 cells assessed as effect on H3K36me2 protein level at 1 to 10 uM incubated for 3 days by Western blot analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 5. | ALA5124721 | B | Inhibition of NSD2 in human KMS-11 cells assessed as effect on H3K36me2 protein level at 1 to 10 uM incubated for 3 days by Western blot analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 6. | ALA5124722 | B | Inhibition of NSD2 in human KMS-11 cells assessed as decrease in PAK1 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 7. | ALA5124723 | B | Inhibition of NSD2 in human RS4-11 cells assessed as decrease in PAK1 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 8. | ALA5124724 | B | Inhibition of NSD2 in human KMS-11 cells assessed as decrease in RRAS2 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 9. | ALA5124725 | B | Inhibition of NSD2 in human RS4-11 cells assessed as decrease in RRAS2 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 10. | ALA5124726 | B | Inhibition of NSD2 in human KMS-11 cells assessed as decrease in TGFA gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 11. | ALA5124727 | B | Inhibition of NSD2 in human RS4-11 cells assessed as decrease in TGFA gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 12. | ALA5124728 | B | Inhibition of NSD2 in human KMS-11 cells assessed as decrease in TEMEL2 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 13. | ALA5124729 | B | Inhibition of NSD2 in human RS4-11 cells assessed as decrease in TEMEL2 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 14. | ALA5124730 | B | Inhibition of NSD2 in human KMS-11 cells assessed as decrease in NCAM1 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 15. | ALA5124731 | B | Inhibition of NSD2 in human RS4-11 cells assessed as decrease in NCAM1 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 16. | ALA5124732 | B | Inhibition of NSD2 in human KMS-11 cells assessed as decrease in HSPG2 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 17. | ALA5124733 | B | Inhibition of NSD2 in human RS4-11 cells assessed as decrease in HSPG2 gene expression at 10 uM incubated for 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 18. | ALA5124734 | F | Antiproliferative activity against human RS4-11 cells assessed as inhibition of cell proliferation measured after 6 days by CCK8 assay | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 19. | ALA5124735 | F | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation measured after 6 days by CCK8 assay | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature | |
| 20. | ALA5124736 | F | Antiproliferative activity against human KMS-11 cells assessed as inhibition of cell proliferation measured after 6 days by CCK8 assay | Homo sapiens | 1 | ALA5120900 | cell-based format | Scientific Literature |
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