# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5106974 | B | Inhibition of Clostridium histolyticum collagenase unit of ColG at 100 uM relative to control | Hathewaya histolytica | 6 | single protein format | Scientific Literature | ||
2. | ALA5106983 | B | Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seconds by FRET based assay | Bacillus cereus | 13 | cell-based format | Scientific Literature | ||
3. | ALA5106987 | B | Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColA at 100 uM relative to control | Bacillus cereus | 6 | single protein format | Scientific Literature | ||
4. | ALA5106988 | B | Inhibition of Clostridium histolyticum peptidase unit of CoLH at 100 uM relative to contol | Hathewaya histolytica | 6 | single protein format | Scientific Literature | ||
5. | ALA5106989 | B | Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA5106990 | B | Inhibition of human recombinant MMP-2 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
7. | ALA5106991 | B | Inhibition of human recombinant MMP-3 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
8. | ALA5106992 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA5106993 | T | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA5106994 | T | Cytotoxicity against human NHDF cells assessed as reduction in cell viability | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA5106995 | T | Cytotoxicity against dog MDCK-II cells assessed as reduction in cell viability | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
12. | ALA5106998 | B | Inhibition of full length Bacillus cereus ColQ1 assessed as reduction in Col 1 cleavage at 1.5 to 12.5 uM incubated for 3 hrs by SDS-PAGE analysis | Bacillus cereus | 9 | single protein format | Scientific Literature | ||
13. | ALA5107000 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as suppression of gelatin lysis at 100 uM incubated for 1 to 6 hrs by coomassie brilliant blue staining based zymography analysis | Bacillus cereus | 10 | cell-based format | Scientific Literature | ||
14. | ALA5107004 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as prevention of cell detachment at 25 uM incubated for 1 to 6 hrs by coomassie brilliant blue staining based SDS-PAGE analysis | Bacillus cereus | 2 | cell-based format | Scientific Literature | ||
15. | ALA5107005 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as protection of spindle shape morphology at > 50 uM incubated for 1 to 6 hrs by coomassie brilliant blue staining based SDS-PAGE analysis | Bacillus cereus | 2 | cell-based format | Scientific Literature | ||
16. | ALA5107006 | B | Inhibition of Bacillus cereus collagenase infected in NHDF cells assessed as reduction in LDH release at > 50 uM incubated for 30 mins by LDH assay | Bacillus cereus | 2 | cell-based format | Scientific Literature | ||
17. | ALA5107021 | B | Inhibition of Bacillus cereus AH187 ColQ1 infected in MDCK-II cells assessed as transepithelial electrical resistance at 100 uM incubated for 15 hrs | Bacillus cereus | 4 | cell-based format | Scientific Literature | ||
18. | ALA5107025 | F | In vivo inhibition of Bacillus cereus AH187 ColQ1 infected in Galleria mellonella larvae assessed as increase in survival rate at 100 uM incubated for 3 days | Bacillus cereus | 3 | organism-based format | Scientific Literature | ||
19. | ALA5107026 | F | In vivo inhibition of Bacillus cereus AH187 ColQ1 infected in Galleria mellonella larvae assessed as increase in survival rate at 25 uM incubated for 3 days | Bacillus cereus | 2 | organism-based format | Scientific Literature |