# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5115842 | F | Antiviral activity against hepatitis A virus genotype 1b infected in human Huh-7.5.1 cells assessed as reduction in virus production at 10 uM incubated for 72 hrs by Nano-Glo luciferase assay | Hepatovirus A | 42 | ALA5113410 | organism-based format | Scientific Literature | |
2. | ALA5115843 | T | Cytotoxicity in human Huh-7.5.1 cells assessed as reduction in cell viability at 10 uM incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 8 | ALA5113410 | cell-based format | Scientific Literature | |
3. | ALA5115844 | F | Antiviral activity against hepatitis A virus genotype 1b infected in human Huh-7.5.1 cells assessed as reduction in virus production incubated for 72 hrs by Nano-Glo luciferase assay | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
4. | ALA5115845 | T | Cytotoxicity in human Huh-7.5.1 cells assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 4 | ALA5113410 | cell-based format | Scientific Literature | |
5. | ALA5115846 | T | Selectivity index, ratio of CC50 for Cytotoxicity in human Huh-7.5.1 cells to EC50 for Antiviral activity against hepatitis A virus genotype 1b infected in human Huh-7.5.1 cells | 4 | ALA5113410 | cell-based format | Scientific Literature | ||
6. | ALA5115847 | B | Inhibition of luciferase (unknown origin) at 200 uM | Not specified | 4 | ALA5113410 | assay format | Scientific Literature | |
7. | ALA5115848 | F | Antiviral activity against hepatitis A virus HM175/18f infected in human Huh-7.5.1 cells assessed as reduction in HM175 production at 2 to 50 uM incubated for 72 hrs by RT-qPCR method | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
8. | ALA5115849 | F | Antiviral activity against hepatitis A virus genotype 1b infected in human Huh-7.5.1 cells assessed as reduction in virus production at 10 uM incubated for 24 hrs and then cells were harvested followed by HAV/NLuc infection by Nano-Glo luciferase assay | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
9. | ALA5115850 | F | Antiviral activity against hepatitis A virus genotype 1b infected in human Huh-7.5.1 cells assessed as reduction in virus production at 10 uM incubated for 6 hrs with simultaneous HAV/NLuc infection by Nano-Glo luciferase assay | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
10. | ALA5115851 | F | Antiviral activity against hepatitis A virus genotype 1b infected in human Huh-7.5.1 cells assessed as reduction in virus production at 10 uM incubated for 72 hrs after 6 hrs HAV/NLuc infection by Nano-Glo luciferase assay | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
11. | ALA5115852 | F | Antiviral activity against hepatitis A virus HM175 infected in human Huh-7.5.1 cells assessed as reduction in HAV2c Protein expression at 10 uM incubated for 48 hrs by immunofluorescence assay | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
12. | ALA5115853 | F | Antiviral activity against hepatitis A virus infected in human Huh-7.5.1 cells assessed as reduction in viral RNA replication at 2 to 50 uM incubated for 72 hrs by luciferase reporter dependent subgenomic replicon assay | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
13. | ALA5115854 | F | Antiviral activity against hepatitis A virus KRM031 infected in human Huh-7.5.1 cells assessed as reduction in cytoplasmic viral RNA level at 5 to 20 uM incubated for 72 hrs dosed after infection for 6 hrs by RT-qPCR method | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature | |
14. | ALA5115855 | F | Antiviral activity against hepatitis A virus TICM005 infected in human Huh-7.5.1 cells assessed as reduction in cytoplasmic viral RNA level at 5 to 20 uM incubated for 72 hrs dosed after infection for 6 hrs by RT-qPCR method | Hepatovirus A | 4 | ALA5113410 | organism-based format | Scientific Literature |