# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5124275 | Binding | Inhibition of EP300 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA method | Homo sapiens | 13 | ALA5120873 | single protein format | Scientific Literature | |
2. | ALA5124276 | Functional | Antiproliferative activity against human OPM-2 cells incubated for 5 days by CCK-8 method | Homo sapiens | 5 | ALA5120873 | cell-based format | Scientific Literature | |
3. | ALA5124277 | Functional | Antiproliferative activity against human 22Rv1 cells incubated for 5 days by CCK-8 method | Homo sapiens | 5 | ALA5120873 | cell-based format | Scientific Literature | |
4. | ALA5124278 | Functional | Antiproliferative activity against human MCF7 cells incubated for 5 days by CCK-8 method | Homo sapiens | 5 | ALA5120873 | cell-based format | Scientific Literature | |
5. | ALA5124279 | Functional | Antiproliferative activity against human SCC-9 cells incubated for 5 days by CCK-8 method | Homo sapiens | 5 | ALA5120873 | cell-based format | Scientific Literature | |
6. | ALA5124281 | Binding | Inhibition of EP300/CBP bromodomain in human OPM-2 cells assessed as suppression of c-myc expression at <= 1 uM incubated for 3 days by Western blot analysis | Homo sapiens | 2 | ALA5120873 | cell-based format | Scientific Literature | |
7. | ALA5124285 | Functional | Induction of cell cycle arrest in human OPM-2 cells assessed as accumulation of cells at G1/G0 phase at 5 uM incubated for 48 hrs by PI staining based flow cytometry analysis (Rvb = 34.25 %) | Homo sapiens | 3 | ALA5120873 | cell-based format | Scientific Literature | |
8. | ALA5124286 | Functional | Induction of apoptosis in human OPM-2 cells assessed as apoptotic cells at 3 uM incubated for 72 hrs by annexin V-FITC/PI staining based flow cytometry analysis | Homo sapiens | 3 | ALA5120873 | cell-based format | Scientific Literature |