| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5124518 | B | Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as decrease in BCL-XL protein level pretreated with MG132 for 1 hr followed by compound addition and measured after 6 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5120886 | cell-based format | Scientific Literature | |
| 2. | ALA5124519 | B | Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as decrease in BCL-XL protein level by measuring maximum degradation at 1 uM pretreated with MG132 for 1 hr followed by compound addition and measured after 6 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | ALA5120886 | cell-based format | Scientific Literature | |
| 3. | ALA5124520 | B | Protac activity at VHL/BCL-XL in human platelets assessed as decrease in BCL-XL protein level measured after 6 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5120886 | cell-based format | Scientific Literature | |
| 4. | ALA5124521 | B | Protac activity at VHL/BCL-XL in human platelets assessed as decrease in BCL-XL protein level by measuring maximum degradation at 1 uM measured after 6 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | ALA5120886 | cell-based format | Scientific Literature | |
| 5. | ALA5124522 | F | Cytotoxicity against human MOLT-4 cells assessed as cell viability treated for 72 hrs by MTS assay | Homo sapiens | 1 | ALA5120886 | cell-based format | Scientific Literature |
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