# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5123560 | B | Inhibition of human PARP-10 using NAD+ as substrate incubated for 10 mins by fluorescence based analysis | Homo sapiens | 22 | ALA5120855 | single protein format | Scientific Literature | |
2. | ALA5123561 | B | Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate incubated for 10 mins by fluorescence based analysis | Homo sapiens | 22 | ALA5120855 | cell-based format | Scientific Literature | |
3. | ALA5123562 | B | Inhibition of human PARP14 using NAD+ as substrate incubated for 10 mins by fluorescence based analysis | Homo sapiens | 22 | ALA5120855 | single protein format | Scientific Literature | |
4. | ALA5123563 | B | Inhibition of human PARP2 using NAD+ as substrate incubated for 10 mins by fluorescence based analysis | Homo sapiens | 22 | ALA5120855 | single protein format | Scientific Literature | |
5. | ALA5123564 | B | Inhibition of human N-terminal 6His-tagged TNKS2 (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate incubated for 10 mins by fluorescence based analysis | Homo sapiens | 22 | ALA5120855 | cell-based format | Scientific Literature | |
6. | ALA5123565 | B | Inhibition of human PARP-1 using NAD+ as substrate incubated for 10 mins by fluorescence based analysis | Homo sapiens | 4 | ALA5120855 | single protein format | Scientific Literature | |
7. | ALA5123566 | B | Inhibition of human PARP3 | Homo sapiens | 4 | ALA5120855 | single protein format | Scientific Literature | |
8. | ALA5123567 | B | Inhibition of human PARP4 | Homo sapiens | 4 | ALA5120855 | single protein format | Scientific Literature | |
9. | ALA5123568 | B | Inhibition of human TNKS1 | Homo sapiens | 4 | ALA5120855 | single protein format | Scientific Literature | |
10. | ALA5123569 | B | Inhibition of human PARP12 | Homo sapiens | 4 | ALA5120855 | single protein format | Scientific Literature | |
11. | ALA5123570 | B | Inhibition of human PARP16 | Homo sapiens | 4 | ALA5120855 | single protein format | Scientific Literature | |
12. | ALA5123571 | T | Cytotoxicity against HEK293T cells assessed as reduction in cell viability at 10 uM measured after 24 hrs by WST-1 assay | Homo sapiens | 22 | ALA5120855 | cell-based format | Scientific Literature | |
13. | ALA5123573 | F | Rescue of cell viability in human HeLa cells expressing wild type PARP10 at upto 10 uM incubated for 10 to 12 days by methylene blue dye based colony formation assay | Homo sapiens | 4 | ALA5120855 | cell-based format | Scientific Literature | |
14. | ALA5123574 | F | Rescue of cell viability in human HeLa cells expressing PARP10-G888W mutant at upto 10 uM incubated for 10 to 12 days by methylene blue dye based colony formation assay | Homo sapiens | 4 | ALA5120855 | cell-based format | Scientific Literature |