# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5116434 | B | Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication | Hepatitis B virus | 25 | ALA5113429 | cell-based format | Scientific Literature | |
2. | ALA5116435 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 19 | ALA5113429 | microsome format | Scientific Literature | |
3. | ALA5116436 | P | Thermodynamic solubility in pH 7 buffer | 18 | ALA5113429 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5116437 | B | Ratio of EC50 for modulation of capsid assembly in HBV infected in human HepG2.2.15 cells in presence of 40% normal human serum to EC50 for modulation of capsid assembly in HBV infected in human HepG2.2.15 cells in absence of 40% normal human serum | Hepatitis B virus | 2 | ALA5113429 | cell-based format | Scientific Literature | |
5. | ALA5116438 | A | Intrinsic clearance in rat liver microsomes | Rattus norvegicus | 2 | ALA5113429 | microsome format | Scientific Literature | |
6. | ALA5116439 | A | Intrinsic clearance in mouse liver microsomes | Mus musculus | 1 | ALA5113429 | microsome format | Scientific Literature | |
7. | ALA5116440 | A | Intrinsic clearance in dog liver microsomes | Canis lupus familiaris | 2 | ALA5113429 | microsome format | Scientific Literature | |
8. | ALA5116441 | P | Lipophilicity, log D of compound | 2 | ALA5113429 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA5116442 | A | Protein binding in human plasma | Homo sapiens | 1 | ALA5113429 | cell-free format | Scientific Literature | |
10. | ALA5116443 | A | Protein binding in rat plasma | Rattus norvegicus | 1 | ALA5113429 | cell-free format | Scientific Literature | |
11. | ALA5116444 | A | Protein binding in mouse plasma | Mus musculus | 1 | ALA5113429 | cell-free format | Scientific Literature | |
12. | ALA5116445 | A | Protein binding in dog plasma | Canis lupus familiaris | 1 | ALA5113429 | cell-free format | Scientific Literature | |
13. | ALA5116446 | A | Intrinsic clearance in human hepatocytes | Homo sapiens | 1 | ALA5113429 | cell-based format | Scientific Literature | |
14. | ALA5116447 | A | Intrinsic clearance in dog hepatocytes | Canis lupus familiaris | 1 | ALA5113429 | cell-based format | Scientific Literature | |
15. | ALA5116448 | A | Intrinsic clearance in rat hepatocytes | Rattus norvegicus | 1 | ALA5113429 | cell-based format | Scientific Literature | |
16. | ALA5116449 | A | Intrinsic clearance in mouse hepatocytes | Mus musculus | 1 | ALA5113429 | cell-based format | Scientific Literature | |
17. | ALA5116450 | A | Plasma clearance in mouse at 10 mg/kg, po or 2.5 mg/kg, iv | Mus musculus | 1 | ALA5113429 | organism-based format | Scientific Literature | |
18. | ALA5116451 | A | Volume of distribution at steady state in mouse at 10 mg/kg, po or 2.5 mg/kg, iv | Mus musculus | 1 | ALA5113429 | organism-based format | Scientific Literature | |
19. | ALA5116452 | A | Half life in mouse at 10 mg/kg, po or 2.5 mg/kg, iv | Mus musculus | 1 | ALA5113429 | organism-based format | Scientific Literature | |
20. | ALA5116453 | A | Cmax in mouse at 10 mg/kg, po | Mus musculus | 1 | ALA5113429 | organism-based format | Scientific Literature |