#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5136927	Binding	Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM incubated for 5 mins by microscale thermophoresis assay	Homo sapiens	38	ALA5131574	assay format	Scientific Literature
2.	ALA5136928	Binding	Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM using tRNA asp as substrate and SAM as co-substrate incubated for 5 mins by tritium incorporation assay relative to control	Homo sapiens	38	ALA5131574	assay format	Scientific Literature
3.	ALA5136929	Binding	Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant at 100 uM by isothermal titration calorimetry assay	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
4.	ALA5136930	Binding	Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry assay	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
5.	ALA5136932	Binding	Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as gibbs free energy change at 100 uM by isothermal titration calorimetry assay	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
6.	ALA5136933	Binding	Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as change in enthalpy change at 100 uM by isothermal titration calorimetry assay	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
7.	ALA5136934	Binding	Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as change in entropy at 100 uM by isothermal titration calorimetry assay	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
8.	ALA5136935	Binding	Inhibition of recombinant human DNMT3A-3L expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM using Poly(dI-dC)-Poly(dI-dC) as substrate measured at 150 mins by liquid scintillation counting analysis	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
9.	ALA5136936	Binding	Inhibition of full length recombinant human NSUN2 expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM measured at 20 mins by liquid scintillation counting analysis	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
10.	ALA5136937	Binding	Inhibition of full length human NSUN6 expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM measured at 20 mins by liquid scintillation counting analysis	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
11.	ALA5136938	Binding	Inhibition of recombinant human EHMT2 G9a expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM using histone H3 as substrate measured at 120 mins by liquid scintillation counting analysis	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
12.	ALA5136939	Binding	Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM by liquid scintillation counting analysis	Homo sapiens	6	ALA5131574	assay format	Scientific Literature
13.	ALA5136941	Toxicity	Cytotoxicity against human HEK293 cells assessed as cell viability at 100 uM measured after 24 hrs by MTT assay	Homo sapiens	4	ALA5131574	cell-based format	Scientific Literature
14.	ALA5136944	ADME	Permeability of the compound in human Caco-2 cells assessed as compound remaining by measuring ester form of the acceptor compartment incubated for 24 hrs by LC/MS analysis	Homo sapiens	2	ALA5131574	cell-based format	Scientific Literature