| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5124650 | T | Cytotoxicity against mouse C8D1A cells assessed as cell viability at 0.75 to 50 uM after 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5124651 | F | Inhibition of LPS-induced mouse C8D1A cell viability loss assessed as restoration of cell viability at 0.75 to 6 uM after 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5124652 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced NO production measured after 24 hrs by Griess method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5124653 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced iNOS production by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5124654 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced ROS production measured after 24 hrs by fluorescent CM-H2DCFDA based flow cytometry | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5124655 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-6 production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5124656 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-1beta production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5124657 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced TNFalpha production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5124658 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-6 mRNA expression at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by real time PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5124659 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced IL-1beta mRNA expression at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by real time PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5124660 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced TNFalpha mRNA expression at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by real time PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5124661 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced GFAP production at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by DMI-8 microscopy | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5124662 | B | Inhibition of IKKalpha/beta phosphorylation at Ser176/180 in LPS-induced mouse C8D1A cells at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5124663 | B | Inhibition of IkappaBalpha phosphorylation at Ser176/180 in LPS-induced mouse C8D1A cells at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5124664 | B | Inhibition of NFkappaB p65 phosphorylation at Ser176/180 in LPS-induced mouse C8D1A cells at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5124665 | F | Effect on LPS-induced inflammasome activation in mouse C8D1A cells assessed as reduction in NLRP3 protein level at 0.75 to 3 uM by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5124666 | F | Effect on LPS-induced inflammasome activation in mouse C8D1A cells assessed as reduction in caspase 1 protein level at 0.75 to 3 uM by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5124667 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced NO production at 3 uM measured after 24 hrs by Griess method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5124668 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced iNOS expression at 3 uM by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5124669 | F | Antiinflammatory activity against mouse C8D1A cells assessed as inhibition of LPS-induced NO production at 3 uM measured after 24 hrs in presence of Y1R antagonist BIBP3226 by Griess method | Mus musculus | 1 | cell-based format | Scientific Literature |
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