# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5168188 | Functional | Increase in intracellular fluconazole accumulation in wild type Candida albicans SC5314 at 1 ug/ml incubated for 1 hr by fluorescence based analysis | Candida albicans | 1 | ALA5154933 | cell-based format | Scientific Literature | |
2. | ALA5168189 | Toxicity | Toxicity against Galleria mellonella larva infected with Candida albicans SC5314 assessed as increase in survival rate at 8 mg/kg measured for 14 days | Galleria mellonella | 2 | ALA5154933 | organism-based format | Scientific Literature | |
3. | ALA5168190 | Functional | Potentiation of antifungal activity against fluconazole-sensitive Candida albicans YEM12 overexpressing efflux pump MDR1 gene assessed as fold reduction in fluconazole MIC at 1 ug/ml incubated for 24 hrs by checkerboard broth microdilution assay | Candida albicans | 1 | ALA5154933 | organism-based format | Scientific Literature | |
4. | ALA5168191 | Functional | Antifungal activity against Cryptococcus neoformans H99 assessed as fungal growth inhibition by broth microdilution assay | Cryptococcus neoformans | 6 | ALA5154933 | organism-based format | Scientific Literature | |
5. | ALA5168192 | Functional | Antifungal activity against Cryptococcus neoformans 5-FC assessed as fungal growth inhibition by broth microdilution assay | Cryptococcus neoformans | 6 | ALA5154933 | organism-based format | Scientific Literature | |
6. | ALA5168193 | Functional | Antifungal activity against Cryptococcus gattii VGII R265 assessed as fungal growth inhibition by broth microdilution assay | Cryptococcus gattii species complex | 6 | ALA5154933 | organism-based format | Scientific Literature | |
7. | ALA5168194 | Functional | Antifungal activity against Candida albicans SC5314 assessed as fungal growth inhibition by broth microdilution assay | Candida albicans | 6 | ALA5154933 | organism-based format | Scientific Literature | |
8. | ALA5168195 | Functional | Antifungal activity against Candida albicans CARG5 assessed as fungal growth inhibition by broth microdilution assay | Candida albicans | 6 | ALA5154933 | organism-based format | Scientific Literature | |
9. | ALA5168196 | Functional | Antifungal activity against Candida albicans CA17 assessed as fungal growth inhibition by broth microdilution assay | Candida albicans | 6 | ALA5154933 | organism-based format | Scientific Literature | |
10. | ALA5168197 | Functional | Antifungal activity against Candida albicans 28A assessed as fungal growth inhibition by broth microdilution assay | Candida albicans | 6 | ALA5154933 | organism-based format | Scientific Literature | |
11. | ALA5168198 | Functional | Antifungal activity against Candida parapsilosis ATCC 22019 assessed as fungal growth inhibition by broth microdilution assay | Candida parapsilosis | 6 | ALA5154933 | organism-based format | Scientific Literature | |
12. | ALA5168199 | Functional | Antifungal activity against Candida krusei ATCC6258 assessed as fungal growth inhibition by broth microdilution assay | Pichia kudriavzevii | 6 | ALA5154933 | organism-based format | Scientific Literature | |
13. | ALA5168200 | Functional | Antifungal activity against Mucor racemosus MZ140 assessed as fungal growth inhibition by broth microdilution assay | Mucor racemosus | 4 | ALA5154933 | organism-based format | Scientific Literature | |
14. | ALA5168201 | Functional | Antifungal activity against Mucor racemosus R715 assessed as fungal growth inhibition by broth microdilution assay | Mucor racemosus | 4 | ALA5154933 | organism-based format | Scientific Literature | |
15. | ALA5168202 | Functional | Antifungal activity against Aspergillus fumigatus AF293 assessed as fungal growth inhibition by broth microdilution assay | Aspergillus fumigatus | 4 | ALA5154933 | organism-based format | Scientific Literature | |
16. | ALA5168203 | Functional | Antifungal activity against Aspergillus fumigatus shjt40 assessed as fungal growth inhibition by broth microdilution assay | Aspergillus fumigatus | 4 | ALA5154933 | organism-based format | Scientific Literature | |
17. | ALA5168204 | Toxicity | Hemolytic activity in human RBC incubated for 1 hr by microplate reader method | Homo sapiens | 5 | ALA5154933 | cell-based format | Scientific Literature | |
18. | ALA5168205 | Functional | Fungicidal activity against Candida albicans SC5314 assessed as fungal growth inhibition incubated for 24 hrs by resazurin dye based assay | Candida albicans | 2 | ALA5154933 | organism-based format | Scientific Literature | |
19. | ALA5168206 | Toxicity | Selectivity ratio of HC50 for hemolytic activity in human RBC to MIC for antifungal activity against Cryptococcus neoformans H99 | 5 | ALA5154933 | assay format | Scientific Literature | ||
20. | ALA5168207 | Toxicity | Selectivity ratio of HC50 for hemolytic activity in human RBC to MIC for antifungal activity against Cryptococcus neoformans 5-FC | 5 | ALA5154933 | assay format | Scientific Literature |