#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5111529	B	Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins followed by DNA and dNTP addition and measured after 120 mins by Picogreen dye fluorescence intensity analysis	Homo sapiens	48	ALA5108047	cell-based format	Scientific Literature
2.	ALA5111531	A	AUC in CD-1 mouse at 20 mg/kg, po measured upto 24 hrs by reverse phase LCMS analysis	Mus musculus	11	ALA5108047	organism-based format	Scientific Literature
3.	ALA5111532	A	Plasma protein binding in mouse assessed as unbound fraction by equilibrium dailysis	Mus musculus	11	ALA5108047	cell-free format	Scientific Literature
4.	ALA5111533	B	Inhibition of N-terminal His8-tagged/C-terminal FLAG-tagged full length human DNA polymerase theta ( 1 to 2590 residues) polymerase activity expressed in HEK2936E cells	Homo sapiens	1	ALA5108047	cell-based format	Scientific Literature
5.	ALA5111534	B	Inhibition of N-terminal His8-tagged/C-terminal FLAG-tagged full length human DNA polymerase theta ( 1 to 2590 residues) ATPase activity expressed in HEK2936E cells	Homo sapiens	1	ALA5108047	cell-based format	Scientific Literature
6.	ALA5111535	B	Inhibition of human DNA polymerase alpha	Homo sapiens	1	ALA5108047	single protein format	Scientific Literature
7.	ALA5111536	B	Inhibition of human DNA polymerase epsilon	Homo sapiens	1	ALA5108047	assay format	Scientific Literature
8.	ALA5111537	B	Inhibition of human DNA polymerase gamma	Homo sapiens	1	ALA5108047	single protein format	Scientific Literature
9.	ALA5111538	B	Inhibition of human DNA polymerase nu	Homo sapiens	1	ALA5108047	single protein format	Scientific Literature
10.	ALA5111539	B	Inhibition of human DNA polymerase mu	Homo sapiens	1	ALA5108047	single protein format	Scientific Literature
11.	ALA5111540	B	Inhibition of human DNA polymerase lambda	Homo sapiens	1	ALA5108047	single protein format	Scientific Literature
12.	ALA5111541	F	Inhibition of MMEJ-mediated DNA repair in CRSIPRR/Cas9-induced wildtype human HCT-116 cells incubated for 24 hrs by PCR analysis	Homo sapiens	1	ALA5108047	cell-based format	Scientific Literature
13.	ALA5111542	B	Inhibition of DNA polymerase theta in LIG4 knock out HEK293T cells assessed as decrease in MMEJ-mediated DNA repair preincubated for 1 day followed by lentivirus solution addition for 24 hrs prior to media replacement with compound and measured after 96 hrs by flow cytometry based traffic-light reporter assay	Homo sapiens	1	ALA5108047	cell-based format	Scientific Literature
14.	ALA5111543	F	Antiproliferative activity against BRCA2 knock out human HCT-116 cells assessed as inhibition of cell growth incubated for 12 to 14 days with media replacement for every 3 or 4 days	Homo sapiens	1	ALA5108047	cell-based format	Scientific Literature
15.	ALA5111544	F	Antiproliferative activity against BRCA2 knock in human HCT-116 cells assessed as inhibition of cell growth incubated for 7 days with media replacement for every 3 or 4 days	Homo sapiens	1	ALA5108047	cell-based format	Scientific Literature
16.	ALA5111545	A	fCaverage in CD-1 mouse	Mus musculus	11	ALA5108047	assay format	Scientific Literature
17.	ALA5111546	A	Apparent permeability of compound in wild type MDCK cells	Canis lupus familiaris	1	ALA5108047	cell-based format	Scientific Literature
18.	ALA5111547	A	Efflux ratio of apparent permeability in wild type MDCK cells	Canis lupus familiaris	1	ALA5108047	cell-based format	Scientific Literature
19.	ALA5111548	A	Clearance in CD-1 mouse at 2.5 mg/kg, po or 2.5 mg/kg, iv measured upto 24 hrs by reverse phase LCMS analysis	Mus musculus	1	ALA5108047	organism-based format	Scientific Literature
20.	ALA5111549	A	Volume of distribution at steady state in CD-1 mouse at 2.5 mg/kg, po or 2.5 mg/kg, iv measured upto 24 hrs by reverse phase LCMS analysis	Mus musculus	1	ALA5108047	organism-based format	Scientific Literature