# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5107689 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MOLM-14 cells assessed as decrease in FLT3 protein expression at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA5107690 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as decrease in FLT3 protein expression at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA5107710 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MOLM-14 cells assessed as decrease in IKZF1 protein expression at 0.01 to 0.3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA5107711 | B | PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as decrease in IKZF1 protein expression at 0.01 to 0.3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |