| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5119229 | F | Positive allosteric modulation of D1R expressed in human SK-N-MC cells assessed as potentiation of DA-induced cAMP production pretreated with compound for 15 mins followed by dopamine addition measured after 15 mins by HTRF assay relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 2. | ALA5119230 | F | Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production by measuring maximum increase pretreated with compound for 15 mins followed by dopamine EC70 addition measured after 15 mins by HTRF assay relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 3. | ALA5119231 | F | Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound for 15 mins followed by dopamine EC70 addition measured after 15 mins by HTRF assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 4. | ALA5119241 | F | Positive allosteric modulation of human D2R in transfected cells assessed as potentiation of DA-induced cAMP production by measuring maximum efficacy at 10 uM pretreated with compound for 15 mins followed by dopamine addition measured after 15 mins by HTRF assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5119242 | F | Positive allosteric modulation of human D3R in transfected cells assessed as potentiation of DA-induced cAMP production by measuring maximum efficacy at 10 uM pretreated with compound for 15 mins followed by dopamine addition measured after 15 mins by HTRF assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5119243 | F | Positive allosteric modulation of human D4R in transfected cells assessed as potentiation of DA-induced cAMP production by measuring maximum efficacy at 10 uM pretreated with compound for 15 mins followed by dopamine addition measured after 15 mins by HTRF assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5119244 | F | Positive allosteric modulation of human D5R in transfected cells assessed as potentiation of DA-induced cAMP production by measuring maximum efficacy at 10 uM pretreated with compound for 15 mins followed by dopamine addition measured after 15 mins by HTRF assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5119245 | B | Displacement of [3H]SCH-23390 from human D2R in transfected cells at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5119246 | B | Displacement of [3H]SCH-23390 from human D3R in transfected cells at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5119247 | B | Displacement of [3H]SCH-23390 from human D4R in transfected cells at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5119248 | B | Displacement of [3H]SCH-23390 from human D5R in transfected cells at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5119249 | B | Competitive binding affinity to human D5R in transfected cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5119250 | B | Competitive binding affinity to human D4R in transfected cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5119251 | B | Competitive binding affinity to human D3R in transfected cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5119252 | B | Competitive binding affinity to human D2R in transfected cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5119253 | F | Positive allosteric modulation of D1R (unknown origin) expressed in mouse CAD cells assessed as potentiation of DA-induced cAMP production relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5119254 | F | Positive allosteric modulation of D1R (unknown origin) expressed in human SK-N-MC cells assessed as potentiation of DA-induced cAMP production pretreated with compound for 15 mins followed by dopamine addition measured after 15 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5119255 | F | Positive allosteric modulation of D1R (unknown origin) expressed in human SK-N-MC cells assessed as effect on cAMP production pretreated with compound for 15 mins absence of dopamine measured after 15 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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