# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5098928 | Functional | Induction of cell proliferation of human CD4+ve Th cells at 50 uM measured after 96 hrs in presence of alprazolam by flow cytometry analysis relative to control | Homo sapiens | 1 | ALA5096209 | cell-based format | Scientific Literature | |
2. | ALA5098930 | Binding | Displacement of [3H]-muscimol from rat cortical synaptic membrane GABAA receptor assessed as inhibition constant by microscint-scintillation method | Rattus norvegicus | 21 | ALA5096209 | cell membrane format | Scientific Literature | |
3. | ALA5098933 | Binding | Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
4. | ALA5098934 | Binding | Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
5. | ALA5098935 | Binding | Antagonist activity at human alpha6beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
6. | ALA5098936 | Binding | Antagonist activity at human alpha1beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
7. | ALA5098937 | Binding | Antagonist activity at human alpha2beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
8. | ALA5098938 | Binding | Antagonist activity at human alpha2beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
9. | ALA5098939 | Binding | Antagonist activity at human alpha3beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
10. | ALA5098940 | Binding | Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
11. | ALA5098948 | Binding | Receptor occupancy at human GABA receptor | Homo sapiens | 1 | ALA5096209 | assay format | Scientific Literature | |
12. | ALA5098950 | ADME | Apparent permeability of compound across apical to basolateral side in MDCK cells | Canis lupus familiaris | 1 | ALA5096209 | cell-based format | Scientific Literature | |
13. | ALA5098951 | ADME | Apparent permeability of compound across basolateral to apical side in MDCK cells | Canis lupus familiaris | 1 | ALA5096209 | cell-based format | Scientific Literature | |
14. | ALA5098952 | ADME | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in MDCK | Canis lupus familiaris | 1 | ALA5096209 | cell-based format | Scientific Literature | |
15. | ALA5098955 | Functional | Induction of cell proliferation of human CD8-positive T cells at 50 uM measured after 96 hrs in presence of alprazolam by flow cytometry analysis relative to control | Homo sapiens | 1 | ALA5096209 | cell-based format | Scientific Literature | |
16. | ALA5098960 | Functional | Induction of cell proliferation of mouse CD8-positive T cells at 50 uM measured after 48 hrs in presence of alprazolam by flow cytometry analysis relative to control | Mus musculus | 1 | ALA5096209 | cell-based format | Scientific Literature | |
17. | ALA5098961 | Functional | Induction of cell proliferation of mouse CD4+ve Th cells at 50 uM measured after 48 hrs in presence of alprazolam by flow cytometry analysis relative to control | Mus musculus | 1 | ALA5096209 | cell-based format | Scientific Literature | |
18. | ALA5098964 | Binding | Antagonist activity at human GAT1 expressed in CHO cells assessed as [3H]GABA uptake at 50 uM incubated for 3 mins by top-counter microplate scintillation counter assay | Homo sapiens | 1 | ALA5096209 | cell-based format | Scientific Literature | |
19. | ALA5098965 | Binding | Antagonist activity at human GAT2 expressed in CHO cells assessed as [3H]GABA uptake at 50 uM incubated for 3 mins by top-counter microplate scintillation counter assay | Homo sapiens | 1 | ALA5096209 | cell-based format | Scientific Literature | |
20. | ALA5098966 | Binding | Antagonist activity at human BGT1 expressed in CHO cells assessed as [3H]GABA uptake at 50 uM incubated for 3 mins by top-counter microplate scintillation counter assay | Homo sapiens | 1 | ALA5096209 | cell-based format | Scientific Literature |