| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5138538 | B | Inhibition of human recombinant full-length DNMT1 expressed in Sf9 cells assessed as inhibition of methylated dI-dC formation using poly dI-dC and [Me-3H]SAM as substrate incubated for 2 hrs by liquid scintillation counting analysis | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 2. | ALA5138548 | B | Inhibition of human C-terminal domain DNMT3b catalytic domain (568 to 853 residues) expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as inhibition of methylated dI-dC formation using poly dI-dC and [Me-3H]SAM as substrate incubated for 45 mins in presence of DNMT3L by liquid scintillation counting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA5138549 | B | Selectivity ratio of IC50 for human C-terminal domain DNMT3b catalytic domain (568 to 853 residues) expressed in Escherichia coli BL21 (DE3) pLysS cells to IC50 for human recombinant full-length DNMT1 expressed in Sf9 cells | Homo sapiens | 5 | cell-based format | Scientific Literature |
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