| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5164280 | F | Cytotoxicity against human IGROV-1 cells assessed as reduction in cell viability incubated for 24 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 2. | ALA5164281 | T | Toxicity in NSG mouse xenografted with human ES2 cells assessed as body weight change at 10 mg/kg, ip measured upto 30 days | Mus musculus | 1 | ALA5154854 | organism-based format | Scientific Literature | |
| 3. | ALA5164282 | F | Anti-tumor activity against human ES2 cells xenografted in NSG mouse assessed as reduction in tumor volume at 10 mg/kg, ip measured upto 30 days | Homo sapiens | 1 | ALA5154854 | organism-based format | Scientific Literature | |
| 4. | ALA5164283 | T | Cytotoxicity against HEK-293T cells assessed as inhibition of cell proliferation upto 100 uM incubated for 18 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 5. | ALA5164284 | F | Cytotoxicity against human SH-EP1 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 6. | ALA5164285 | B | Antagonist activity at VDR LBD (unknown origin) using Alexa Fluor 647-labeled SRC2-3 as substrate incubated for 2 hrs in presence of calcitriol by fluorescence polarization assay | Homo sapiens | 3 | ALA5154854 | single protein format | Scientific Literature | |
| 7. | ALA5164286 | B | Agonist activity at VDR LBD (unknown origin) using Alexa Fluor 647-labeled SRC2-3 as substrate incubated for 2 hrs by fluorescence polarization assay | Homo sapiens | 3 | ALA5154854 | single protein format | Scientific Literature | |
| 8. | ALA5164287 | B | Antagonist activity at VDR LBD (unknown origin) transfected in HEK-293T cells assessed as inhibition of 1,25(OH)2D3-induced receptor transactivation incubated for 16 hrs by Bright-Glo luciferase assay | Homo sapiens | 3 | ALA5154854 | cell-based format | Scientific Literature | |
| 9. | ALA5164288 | B | Displacement of CBTF-BODIPY from RXR-alpha LBD (unknown origin) at 0.03125 to 32 uM incubated for 1 hr by fluorescence polarization assay | Homo sapiens | 3 | ALA5154854 | single protein format | Scientific Literature | |
| 10. | ALA5164289 | B | Antagonist activity at PPAR-gamma LBD (unknown origin) using Texas red-labeled DRIP-2 as substrate upto 100 uM incubated for 2 hrs in presence of rosiglitazone by fluorescence polarization assay | Homo sapiens | 3 | ALA5154854 | single protein format | Scientific Literature | |
| 11. | ALA5164290 | B | Agonist activity at PPAR-gamma LBD (unknown origin) using Texas red-labeled DRIP-2 as substrate upto 100 uM incubated for 2 hrs by fluorescence polarization assay | Homo sapiens | 3 | ALA5154854 | single protein format | Scientific Literature | |
| 12. | ALA5164291 | B | Antagonist activity at VDR in human 2008 cells assessed as suppression of RXR-alpha expression at 250 nM incubated for 18 hrs by western blot analysis relative to control | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 13. | ALA5164292 | B | Antagonist activity at VDR in human 2008 cells assessed as suppression of importin-4 expression at 250 nM incubated for 12 to 18 hrs by western blot analysis relative to control | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 14. | ALA5164293 | F | Cytotoxicity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 24 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 15. | ALA5164294 | F | Cytotoxicity against human OVCAR-8 cells assessed as reduction in cell viability incubated for 24 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 16. | ALA5164295 | F | Cytotoxicity against human 2008 cells assessed as reduction in cell viability incubated for 24 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 17. | ALA5164296 | F | Cytotoxicity against human Caov-3 cell line assessed as reduction in cell viability incubated for 24 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 18. | ALA5164297 | F | Cytotoxicity against human OVCAR-3 cells assessed as reduction in cell viability at 0.25 to 1.25 uM incubated for 24 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 19. | ALA5164298 | F | Induction of apoptosis in human 2008 cells assessed as cleaved PARP1 expression levels at 250 nM incubated for 18 hrs by western blot analysis (Rvb = 4%) | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature | |
| 20. | ALA5164299 | F | Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation upto 100 uM incubated for 18 hrs by MTS assay | Homo sapiens | 1 | ALA5154854 | cell-based format | Scientific Literature |
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