# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5155236 | Binding | Inhibition of human EGFR L858R/T790M double mutant expressed in Sf9 insect cells in presence of ATP measured by HTRF assay | Homo sapiens | 6 | ALA5154643 | cell-based format | Scientific Literature | |
2. | ALA5155237 | Binding | Inhibition of human EGFR L858R mutant expressed in Sf9 insect cells in presence of ATP measured by HTRF assay | Homo sapiens | 6 | ALA5154643 | cell-based format | Scientific Literature | |
3. | ALA5155238 | Binding | Inhibition of human EGFR L858R/T790M/C797S mutant expressed in Sf9 insect cells in presence of ATP measured by HTRF assay | Homo sapiens | 6 | ALA5154643 | cell-based format | Scientific Literature | |
4. | ALA5155239 | ADME | Apparent permeability across apical to basolateral side in human Caco-2 cells monolayer | Homo sapiens | 2 | ALA5154643 | cell-based format | Scientific Literature | |
5. | ALA5155240 | Functional | Antiproliferative activity against mouse BaF3 cells expressing wild type EGFR incubated for 72 hrs in absence of cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
6. | ALA5155241 | Binding | Inhibition of wild type human EGFR expressed in Sf9 insect cells in presence of ATP measured by HTRF assay | Homo sapiens | 6 | ALA5154643 | cell-based format | Scientific Literature | |
7. | ALA5155243 | Functional | Antiproliferative activity against mouse BaF3 cells expressing EGFR L858R mutant incubated for 72 hrs in absence of cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
8. | ALA5155244 | Functional | Antiproliferative activity against mouse BaF3 cells expressing EGFR L858R/T790M mutant incubated for 72 hrs in absence of cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
9. | ALA5155245 | Functional | Antiproliferative activity against mouse BaF3 cells expressing EGFR Ex19del/T790M/C797S mutant incubated for 72 hrs in absence of cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
10. | ALA5155246 | Functional | Antiproliferative activity against mouse BaF3 cells expressing wild type EGFR incubated for 72 hrs in presence of 1 ug/ml cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
11. | ALA5155247 | Functional | Antiproliferative activity against mouse BaF3 cells expressing EGFR L858R mutant incubated for 72 hrs in presence of 1 ug/ml cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
12. | ALA5155248 | Functional | Antiproliferative activity against mouse BaF3 cells expressing EGFR L858R/T790M mutant incubated for 72 hrs in presence of 1 ug/ml cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
13. | ALA5155249 | Functional | Antiproliferative activity against mouse BaF3 cells expressing EGFR L858R/T790M/C797S mutant incubated for 72 hrs in presence of 1 ug/ml cetuximab by Cell Titer-Glo assay | Mus musculus | 6 | ALA5154643 | cell-based format | Scientific Literature | |
14. | ALA5155250 | Binding | Displacement of sapitinib-BODIPY tracer from C-terminal NanoLuc-fused full length wild type EGFR (unknown origin) transfected in HEK293T cells incubated for 2 hrs by NanoBRET assay | Homo sapiens | 7 | ALA5154643 | cell-based format | Scientific Literature | |
15. | ALA5155251 | Binding | Inhibition of MKK6 SDTD mutant (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control | Homo sapiens | 1 | ALA5154643 | assay format | Scientific Literature | |
16. | ALA5155252 | Binding | Inhibition of TGFBR2 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control | Homo sapiens | 1 | ALA5154643 | single protein format | Scientific Literature | |
17. | ALA5155253 | Binding | Inhibition of ERBB4 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control | Homo sapiens | 1 | ALA5154643 | single protein format | Scientific Literature | |
18. | ALA5155254 | Binding | Inhibition of MAP4K5 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control | Homo sapiens | 1 | ALA5154643 | single protein format | Scientific Literature | |
19. | ALA5155255 | Binding | Inhibition of MINK1 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control | Homo sapiens | 1 | ALA5154643 | single protein format | Scientific Literature | |
20. | ALA5155256 | Binding | Inhibition of ACK1 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control | Homo sapiens | 1 | ALA5154643 | single protein format | Scientific Literature |