# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5148229 | B | Activation of human recombinant AMPK A2/B2/G1 assessed as increase in AMPK phosphorylation using FL-peptide as substrate incubated for 120 mins by EZ reader method | Homo sapiens | 15 | ALA5143699 | protein complex format | Scientific Literature | |
2. | ALA5148230 | A | Protein binding in serum (unknown origin) assessed as unbound fraction by equilibrium dialysis assay | Not specified | 6 | ALA5143699 | cell-free format | Scientific Literature | |
3. | ALA5148231 | A | Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate | Homo sapiens | 4 | ALA5143699 | microsome format | Scientific Literature | |
4. | ALA5148232 | A | Inhibition of CYP1A2 in human liver microsomes using 7-ethoxyresorufin as substrate | Homo sapiens | 2 | ALA5143699 | microsome format | Scientific Literature | |
5. | ALA5148233 | A | Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate | Homo sapiens | 2 | ALA5143699 | microsome format | Scientific Literature | |
6. | ALA5148234 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate | Homo sapiens | 2 | ALA5143699 | microsome format | Scientific Literature | |
7. | ALA5148235 | A | Inhibition of CYP3A4 in human liver microsomes using terfenedine as substrate | Homo sapiens | 2 | ALA5143699 | microsome format | Scientific Literature | |
8. | ALA5148236 | A | Metabolic stability in human liver microsomes assessed as compound remaining measured after 30 mins | Homo sapiens | 4 | ALA5143699 | microsome format | Scientific Literature | |
9. | ALA5148237 | A | Metabolic stability in rat liver microsomes assessed as compound remaining measured after 30 mins | Rattus norvegicus | 4 | ALA5143699 | microsome format | Scientific Literature | |
10. | ALA5148238 | A | AUC in rat at 1 mg/kg, po | Rattus norvegicus | 4 | ALA5143699 | organism-based format | Scientific Literature | |
11. | ALA5148239 | A | Cmax in rat at 1 mg/kg, po or 0.5 mg/kg, iv | Rattus norvegicus | 4 | ALA5143699 | organism-based format | Scientific Literature | |
12. | ALA5148240 | A | Permeability coefficient of the compound in rat liver at 1 mg/kg, po or 0.5 mg/kg, iv | Rattus norvegicus | 4 | ALA5143699 | organism-based format | Scientific Literature | |
13. | ALA5148241 | A | Permeability coefficient of the compound in rat muscle at 1 mg/kg, po or 0.5 mg/kg, iv | Rattus norvegicus | 4 | ALA5143699 | organism-based format | Scientific Literature | |
14. | ALA5148242 | A | Total clearance in rat at 1 mg/kg, po or 0.5 mg/kg, iv | Rattus norvegicus | 4 | ALA5143699 | organism-based format | Scientific Literature |