# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5106610 | B | Inhibition of human caspase-3 using Ac-Asp-Glu-Val-Asp-pNA as substrate incubated for 60 mins by FRET assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
2. | ALA5106611 | B | Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate addition and measured every 10 sec for 10 mins by FRET assay | Severe acute respiratory syndrome coronavirus 2 | 16 | single protein format | Scientific Literature | ||
3. | ALA5106612 | B | Inhibition of human Cathepsin L using Z-Leu-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
4. | ALA5106613 | B | Inhibition of human Cathepsin F using Z-Phe-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
5. | ALA5106614 | B | Inhibition of human Cathepsin K using Ac-LR-AMC as fluorogenic substrate incubated for 60 mins by FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA5106615 | B | Inhibition of human Cathepsin B using Z-Leu-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA5106617 | F | Antiviral activity against SARS-CoV-2 infected in Vero E6 cells assessed as inhibition of viral replication incubated for 25 to 26 hrs by EliSpot reader based analysis | Severe acute respiratory syndrome coronavirus 2 | 9 | organism-based format | Scientific Literature | ||
8. | ALA5106618 | T | Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability incubated for 26 hrs by celltiter 96 aqueous non-radioactive cell proliferation assay | Chlorocebus sabaeus | 7 | cell-based format | Scientific Literature | ||
9. | ALA5106622 | F | Potency index, ratio of remdesivir EC50 to test compound EC50 for Antiviral activity against SARS-CoV-2 infected in Vero E6 cells assessed as inhibition of viral replication incubated for 25 to 26 hrs by EliSpot reader based analysis | Severe acute respiratory syndrome coronavirus 2 | 2 | organism-based format | Scientific Literature |