# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5140361 | F | Antiviral activity against NNRTI resistant wild type HIV-1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 43 | organism-based format | Scientific Literature | ||
2. | ALA5140362 | T | Cytotoxicity against human MT4 cells assessed as cell growth inhibition incubated for 5 days by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
3. | ALA5140363 | T | Selectivity index, ratio of CC50 for human MT4 cells to EC50 for antiviral activity against NNRTI resistant HIV-1 infected in human MT4 cells | 43 | cell-based format | Scientific Literature | |||
4. | ALA5140364 | F | Antiviral activity against drug-resistant HIV-1 L100I mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 43 | organism-based format | Scientific Literature | ||
5. | ALA5140365 | F | Antiviral activity against drug-resistant HIV-1 K103 N mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 43 | organism-based format | Scientific Literature | ||
6. | ALA5140366 | F | Antiviral activity against drug-resistant HIV-1 Y181C mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 43 | organism-based format | Scientific Literature | ||
7. | ALA5140367 | F | Antiviral activity against drug-resistant HIV-1 Y188L mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 43 | organism-based format | Scientific Literature | ||
8. | ALA5140368 | F | Antiviral activity against drug-resistant HIV-1 E138K mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 43 | organism-based format | Scientific Literature | ||
9. | ALA5140369 | B | Inhibition of recombinant wild-type p66/p51 HIV-1 reverse transcriptase incubated for 40 mins by picogreen dye-based spectrofluorometric analysis | Human immunodeficiency virus 1 | 40 | single protein format | Scientific Literature | ||
10. | ALA5140413 | F | Fold resistance, ratio of EC50 for antiviral activity against drug-resistant HIV-1 L100I mutant infected in human MT4 cells to EC50 for antiviral activity against NNRTI resistant wild type HIV-1 infected in human MT4 cells | 42 | cell-based format | Scientific Literature | |||
11. | ALA5140414 | F | Fold resistance, ratio of EC50 for antiviral activity against drug-resistant HIV-1 K103 N mutant infected in human MT4 cells to EC50 for antiviral activity against NNRTI resistant wild type HIV-1 infected in human MT4 cells | 42 | cell-based format | Scientific Literature | |||
12. | ALA5140415 | F | Fold resistance, ratio of EC50 for antiviral activity against drug-resistant HIV-1 Y181C mutant infected in human MT4 cells to EC50 for antiviral activity against NNRTI resistant wild type HIV-1 infected in human MT4 cells | 42 | cell-based format | Scientific Literature | |||
13. | ALA5140416 | F | Fold resistance, ratio of EC50 for antiviral activity against drug-resistant HIV-1 Y188L mutant infected in human MT4 cells to EC50 for antiviral activity against NNRTI resistant wild type HIV-1 infected in human MT4 cells | 42 | cell-based format | Scientific Literature | |||
14. | ALA5140417 | F | Fold resistance, ratio of EC50 for antiviral activity against drug-resistant HIV-1 E138K mutant infected in human MT4 cells to EC50 for antiviral activity against NNRTI resistant wild type HIV-1 infected in human MT4 cells | 42 | cell-based format | Scientific Literature |