# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5112877 | B | Inhibition of Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21 incubated for 24 hrs by fluorescence polarization based competitive binding analysis | Pseudomonas aeruginosa | 23 | assay format | Scientific Literature | ||
2. | ALA5112878 | B | Binding affinity to Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21 assessed as change in gibbs free energy by isothermal titration calorimetry | Pseudomonas aeruginosa | 2 | assay format | Scientific Literature | ||
3. | ALA5112879 | B | Binding affinity to Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21 assessed as dissociation constant by isothermal titration calorimetry | Pseudomonas aeruginosa | 2 | assay format | Scientific Literature | ||
4. | ALA5112880 | B | Binding affinity to Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21 assessed as change in enthalpy by isothermal titration calorimetry | Pseudomonas aeruginosa | 2 | assay format | Scientific Literature | ||
5. | ALA5112881 | B | Binding affinity to Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21 assessed as change in entropy by isothermal titration calorimetry | Pseudomonas aeruginosa | 2 | assay format | Scientific Literature | ||
6. | ALA5112884 | A | Stability in mouse plasma assessed as half life incubated upto 240 mins by HPLC-MS analysis | Mus musculus | 17 | cell-free format | Scientific Literature | ||
7. | ALA5112885 | A | Stability in human plasma assessed as half life incubated upto 240 mins by HPLC-MS analysis | Homo sapiens | 17 | cell-free format | Scientific Literature | ||
8. | ALA5112886 | A | Plasma protein binding in CD-1 mouse incubated for 30 mins by HPLC-MS analysis | Mus musculus | 15 | cell-free format | Scientific Literature | ||
9. | ALA5112887 | A | Plasma protein binding in human incubated for 30 mins by HPLC-MS analysis | Homo sapiens | 15 | cell-free format | Scientific Literature | ||
10. | ALA5112888 | A | Metabolic stability in mouse liver microsomes assessed as half life measured upto 60 mins in presence of NADPH by HPLC-MS analysis | Mus musculus | 17 | microsome format | Scientific Literature | ||
11. | ALA5112889 | A | Metabolic stability in human liver microsomes assessed as half life measured upto 60 mins in presence of NADPH by HPLC-MS analysis | Homo sapiens | 17 | microsome format | Scientific Literature | ||
12. | ALA5112890 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance measured upto 60 mins in presence of NADPH by HPLC-MS analysis | Mus musculus | 17 | microsome format | Scientific Literature | ||
13. | ALA5112891 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance measured upto 60 mins in presence of NADPH by HPLC-MS analysis | Homo sapiens | 17 | microsome format | Scientific Literature | ||
14. | ALA5112892 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 10 to 1000 nM incubated for 24 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
15. | ALA5112893 | F | Cytotoxicity against human A549 cells at 10 to 1000 nM incubated for 24 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
16. | ALA5112895 | T | Cytotoxicity against CHO cells at 10 to 1000 nM incubated for 24 hrs by MTT assay | Cricetulus griseus | 15 | cell-based format | Scientific Literature |