# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5163773 | Functional | Growth inhibition of human MM1.S cells incubated for 4 days by WST assay | Homo sapiens | 3 | ALA5154839 | cell-based format | Scientific Literature | |
2. | ALA5163780 | Binding | Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant incubated for 24 hrs by fluorescence polarization-based competitive binding assay | Homo sapiens | 19 | ALA5154839 | assay format | Scientific Literature | |
3. | ALA5163783 | Binding | Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) C55A mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant incubated for 24 hrs by fluorescence polarization-based competitive binding assay | Homo sapiens | 3 | ALA5154839 | assay format | Scientific Literature | |
4. | ALA5163785 | Functional | Growth inhibition of human U-937 cells incubated for 4 days by WST assay | Homo sapiens | 3 | ALA5154839 | cell-based format | Scientific Literature | |
5. | ALA5163800 | Functional | Induction of apoptosis in human U-937 cells overexpressing BFL-1 assessed as increase in cytochrome c level incubated for 3 hrs by immunoblotting analysis | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
6. | ALA5163801 | Functional | Induction of apoptosis in human Kasumi 1 cells overexpressing BFL-1 assessed as increase in cytochrome c level at 5 to 40 uM incubated for 3 hrs by immunoblotting analysis | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
7. | ALA5163808 | Functional | Induction of apoptosis in human U-937 cells assessed as phosphatidylserine level measured after 4 hrs by Annexin V staining based flow cytometry analysis | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
8. | ALA5163809 | Functional | Induction of apoptosis in human U-937 cells assessed as early apoptotic cells at 60 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.95 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
9. | ALA5163810 | Functional | Induction of apoptosis in human U-937 cells assessed as early apoptotic cells at 10 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.95 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
10. | ALA5163811 | Functional | Induction of apoptosis in human U-937 cells assessed as late apoptotic cells at 10 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.62 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
11. | ALA5163812 | Functional | Induction of apoptosis in human U-937 cells assessed as necrotic cells at 10 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 0.00 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
12. | ALA5163813 | Functional | Induction of apoptosis in human U-937 cells assessed as early apoptotic cells at 20 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.95 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
13. | ALA5163814 | Functional | Induction of apoptosis in human U-937 cells assessed as late apoptotic cells at 20 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.62 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
14. | ALA5163815 | Functional | Induction of apoptosis in human U-937 cells assessed as necrotic cells at 20 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 0.00 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
15. | ALA5163816 | Functional | Induction of apoptosis in human U-937 cells assessed as early apoptotic cells at 40 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.95 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
16. | ALA5163817 | Functional | Induction of apoptosis in human U-937 cells assessed as late apoptotic cells at 40 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.62 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
17. | ALA5163818 | Functional | Induction of apoptosis in human U-937 cells assessed as necrotic cells at 40 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 0.00 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
18. | ALA5163819 | Functional | Induction of apoptosis in human U-937 cells assessed as late apoptotic cells at 60 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 1.62 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
19. | ALA5163820 | Functional | Induction of apoptosis in human U-937 cells assessed as necrotic cells at 60 uM measured after 4 hrs by Annexin PI staining based flow cytometry method (Rvb = 0.00 %) | Homo sapiens | 2 | ALA5154839 | cell-based format | Scientific Literature | |
20. | ALA5163821 | Functional | Growth inhibition of human Kasumi 1 cells incubated for 4 days by WST assay | Homo sapiens | 3 | ALA5154839 | cell-based format | Scientific Literature |