| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5136647 | T | Cytotoxicity against human Calu-3 cells assessed as reduction in cell virion production at 10 uM incubated for 24 hrs by cell titer glo luminescent assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 2. | ALA5136648 | B | Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 using Boc-Abu-Tle-Leu-Gln-AMC37 as fluorogenic substrate pre-incubated for 5 mins followed by substrate addition measured after 60 mins by FRET based assay | Severe acute respiratory syndrome coronavirus 2 | 33 | assay format | Scientific Literature | ||
| 3. | ALA5136650 | B | Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Leu-Gln-AMC37 as fluorogenic substrate pre-incubated for 5 mins followed by substrate addition measured after 60 mins by FRET based assay | Severe acute respiratory syndrome coronavirus 2 | 29 | assay format | Scientific Literature | ||
| 4. | ALA5136651 | B | Time dependent inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as ratio of Kinact/Ki using MCA-AVLQSGFR-K(DNP)-K-NH2 as substrate pre-incubated for 5 mins followed by substrate addition measured after 60 mins by FRET based assay | Severe acute respiratory syndrome coronavirus 2 | 33 | assay format | Scientific Literature | ||
| 5. | ALA5136652 | T | Cytotoxicity against African green monkey Vero 76 cells assessed as reduction in cell virion production at 10 uM incubated for 24 hrs by cell titer glo luminescent assay | Chlorocebus sabaeus | 19 | cell-based format | Scientific Literature | ||
| 6. | ALA5136655 | B | Inhibition of recombinant SARS CoV-1 main protease expressed using MCA-AVLQSGFR-K(DNP)-K-NH2 as substrate incubated for 2 hrs by FRET based assay | Severe acute respiratory syndrome-related coronavirus | 17 | assay format | Scientific Literature | ||
| 7. | ALA5136656 | B | Inhibition of MERS-CoV -Mpro using Ac-Abu-Tle-Leu-Gln-ACC as substrate incubated for 2 hrs by FRET based assay | Middle East respiratory syndrome-related coronavirus | 17 | assay format | Scientific Literature |
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