# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5166005 | B | Inhibition of eGFP-tagged rat GluN1/GluN2A transfected in human tsA201 cells assessed as blockade of glycine/NMDA-induced current at 10 uM treated for 40 secs measured at -60 mV holding potential after returning from +60 mV application for 5 secs by whole-cell patch-clamp method relative to control | Rattus norvegicus | 4 | ALA5154888 | cell-based format | Scientific Literature | |
2. | ALA5166006 | B | Inhibition of eGFP-tagged rat GluN1/GluN2A transfected in human tsA201 cells assessed as blockade of glycine/NMDA-induced current at 10 uM treated for 40 secs measured at +60 mV holding potential applied for 5 secs by whole-cell patch-clamp method relative to control | Rattus norvegicus | 3 | ALA5154888 | cell-based format | Scientific Literature | |
3. | ALA5166007 | B | Inhibition of eGFP-tagged rat GluN1/GluN2A transfected in human tsA201 cells assessed as weighted time constant for blockade of glycine/NMDA-induced current at 10 uM at 1 sec by whole-cell patch-clamp method | Rattus norvegicus | 4 | ALA5154888 | cell-based format | Scientific Literature | |
4. | ALA5166008 | B | Inhibition of eGFP-tagged rat GluN1/GluN2A transfected in human tsA201 cells assessed as recovery of glycine/NMDA-induced current at 10 uM treated for 40 secs followed by application of +60 mV holding potential for 5 secs measured after 40 secs of compound removal by whole-cell patch-clamp method relative to control | Rattus norvegicus | 3 | ALA5154888 | cell-based format | Scientific Literature | |
5. | ALA5166009 | B | Inhibition of eGFP-tagged rat GluN1/GluN2A transfected in human tsA201 cells assessed as weighted time constant for recovery of glycine/NMDA-induced current at 10 uM treated for 40 secs followed by application of +60 mV holding potential for 5 secs measured after 40 secs of compound removal by whole-cell patch-clamp method | Rattus norvegicus | 2 | ALA5154888 | cell-based format | Scientific Literature |